Advantages of vitrification preservation in assisted reproduction and potential influences on imprinted genes

H Chen, L Zhang, L Meng, L Liang, C Zhang - Clinical Epigenetics, 2022 - Springer
Cryopreservation has important application in assisted reproductive technology (ART). The
vitrification technique has been widely used in the cryopreservation of oocytes and embryos …

Placental dysfunction in assisted reproductive pregnancies: perinatal, neonatal and adult life outcomes

C Manna, V Lacconi, G Rizzo, A De Lorenzo… - International Journal of …, 2022 - mdpi.com
Obstetric and newborn outcomes of assisted reproductive technology (ART) pregnancies
are associated with significative prevalence of maternal and neonatal adverse health …

Inheritance of paternal lifestyles and exposures through sperm DNA methylation

KW Greeson, KMS Crow, RC Edenfield… - Nature Reviews …, 2023 - nature.com
Many different lifestyle factors and chemicals present in the environment are a threat to the
reproductive tracts of humans. The potential for parental preconception exposure to alter …

A review on epigenetic inheritance of experiences in humans

M Ghai, F Kader - Biochemical Genetics, 2022 - Springer
If genetics defines the inheritance of DNA, epigenetics aims to regulate and make it
adaptable. Epigenetic alterations include DNA methylation, chromatin remodelling, post …

Growth restriction and genomic imprinting-overlapping phenotypes support the concept of an imprinting network

T Eggermann, JH Davies, M Tauber, E van den Akker… - Genes, 2021 - mdpi.com
Intrauterine and postnatal growth disturbances are major clinical features of imprinting
disorders, a molecularly defined group of congenital syndromes caused by molecular …

Placenta-specific genes, their regulation during villous trophoblast differentiation and dysregulation in preterm preeclampsia

A Szilagyi, Z Gelencser, R Romero, Y Xu… - International journal of …, 2020 - mdpi.com
The human placenta maintains pregnancy and supports the developing fetus by providing
nutrition, gas-waste exchange, hormonal regulation, and an immunological barrier from the …

Sex difference in adrenal developmental toxicity induced by dexamethasone and its intrauterine programming mechanism

Y Chen, D Xu, X Xia, G Chen, H Xiao, L Chen… - Pharmacological …, 2021 - Elsevier
Dexamethasone is widely used to treat preterm labor and related diseases. However,
prenatal dexamethasone treatment (PDT) can cause multiorgan developmental toxicities in …

Methylation status of nc886 epiallele reflects periconceptional conditions and is associated with glucose metabolism through nc886 RNAs

S Marttila, LE Viiri, PP Mishra, B Kühnel… - Clinical …, 2021 - Springer
Background Non-coding RNA 886 (nc886) is coded from a maternally inherited metastable
epiallele. We set out to investigate the determinants and dynamics of the methylation pattern …

Why and how imprinted genes drive fetal programming

BJ Crespi - Frontiers in Endocrinology, 2020 - frontiersin.org
Imprinted genes mediate fetal and childhood growth and development, and early growth
patterns drive fetal programming effects. However, predictions and evidence from the …

Sperm cryopreservation and DNA methylation: possible implications for ART success and the health of offspring

Z Khosravizadeh, K Khodamoradi, Z Rashidi… - Journal of assisted …, 2022 - Springer
Despite the beneficial effects of sperm cryopreservation, increased reactive oxygen species
(ROS) production during this process can affect spermatozoon structure and function …