The nucleus is a complex organelle that hosts the genome and is essential for vital
processes like DNA replication, DNA repair, transcription, and splicing. The genome is non …

Nucleoli are dynamic nuclear condensates in eukaryotic cells that originate through
ribosome biogenesis at loci that harbor the ribosomal DNA. These loci are known as …

Centromeres are known to cluster around nucleoli in Drosophila and mammalian cells, but
the significance of the nucleoli–centromere interaction remains underexplored. To …

Senataxin is an evolutionarily conserved RNA-DNA helicase involved in DNA repair and
transcription termination that is associated with human neurodegenerative disorders. Here …

U3 snoRNA is essential for ribosome biogenesis during interphase. Upon mitotic onset, the
nucleolus disassembles and U3 snoRNA relocates to the perichromosomal region (PR) to …

Aim: To investigate the role and function of NOL6, a protein related to ribosome biogenesis,
in endometrial cancer. Methods: Methyl thiazolyl tetrazolium assay, colony formation assay …

BACKGROUND: Cerebral vasospasm (CV) can cause inflammation and damage to
neuronal cells in the elderly, leading to dementia. PURPOSE: This study aimed to …

Abstract Background WD40 repeat (WDR) 43 is an RNA-binding protein that belongs to the
WDR domain protein family. Its biological function is largely unclear, particularly in colorectal …

During interphase, the nucleus contains a multitude of transcripts that influence the function
of chromatin and global structure of the nucleus. Nuclear transcripts include nascent mRNAs …

Background Pulmonary arterial hypertension (PAH) is a devastating chronic
cardiopulmonary disease without an effective therapeutic approach. The underlying …