An update on Cryptosporidium biology and therapeutic avenues
Cryptosporidium species has been identified as an important pediatric diarrheal pathogen in
resource-limited countries, particularly in very young children (0–24 months). However, the …
resource-limited countries, particularly in very young children (0–24 months). However, the …
Use-case scenarios for an anti-Cryptosporidium therapeutic
PG Ashigbie, S Shepherd, KL Steiner… - PLOS Neglected …, 2021 - journals.plos.org
Cryptosporidium is a widely distributed enteric parasite that has an increasingly appreciated
pathogenic role, particularly in pediatric diarrhea. While cryptosporidiosis has likely affected …
pathogenic role, particularly in pediatric diarrhea. While cryptosporidiosis has likely affected …
Metagenomic analysis of gut microbiome and resistome of diarrheal fecal samples from Kolkata, India, reveals the core and variable microbiota including signatures of …
R De, AK Mukhopadhyay, S Dutta - Gut Pathogens, 2020 - Springer
Background Metagenomic analysis of the gut microbiome and resistome is instrumental for
understanding the dynamics of diarrheal pathogenesis and antimicrobial resistance …
understanding the dynamics of diarrheal pathogenesis and antimicrobial resistance …
Associations between ambient temperature and enteric infections by pathogen: a systematic review and meta-analysis
Background Numerous studies have quantified the associations between ambient
temperature and enteric infections, particularly all-cause enteric infections. However, the …
temperature and enteric infections, particularly all-cause enteric infections. However, the …
Burden of Shigella in South Asia: a systematic review and meta-analysis
BA Muzembo, K Kitahara, D Mitra… - Journal of Travel …, 2023 - academic.oup.com
Background Shigella remains one of the most common causes of diarrhoea in South Asia.
Current estimates of the prevalence of Shigella are critical for guiding control measures. We …
Current estimates of the prevalence of Shigella are critical for guiding control measures. We …
Genetic ablation of purine salvage in Cryptosporidium parvum reveals nucleotide uptake from the host cell
MC Pawlowic, M Somepalli… - Proceedings of the …, 2019 - National Acad Sciences
The apicomplexan parasite Cryptosporidium is a leading global cause of severe diarrheal
disease and an important contributor to early-childhood mortality. Waterborne outbreaks …
disease and an important contributor to early-childhood mortality. Waterborne outbreaks …
[HTML][HTML] Dissection of barrier dysfunction in organoid-derived human intestinal epithelia induced by Giardia duodenalis
Background & Aims The protozoa Giardia duodenalis is a major cause of gastrointestinal
illness worldwide, but underlying pathophysiological mechanisms remain obscure, partly …
illness worldwide, but underlying pathophysiological mechanisms remain obscure, partly …
Factors associated with dehydrating rotavirus diarrhea in children under five in Bangladesh: An urban-rural comparison
S Yeasmin, SMT Hasan, MJ Chisti, MA Khan… - Plos one, 2022 - journals.plos.org
Introduction Rotavirus is the leading cause of dehydrating diarrhea in young children
worldwide. This study aimed to identify the factors associated with dehydrating rotavirus …
worldwide. This study aimed to identify the factors associated with dehydrating rotavirus …
Global projections of temperature-attributable mortality due to enteric infections: a modelling study
Background Mortality due to enteric infections is projected to increase because of global
warming; however, the different temperature sensitivities of major enteric pathogens have …
warming; however, the different temperature sensitivities of major enteric pathogens have …
Molecular diversity of Giardia duodenalis in children under 5 years from the Manhiça district, Southern Mozambique enrolled in a matched case-control study on the …
A Messa Jr, PC Köster, M Garrine… - PLoS Neglected …, 2021 - journals.plos.org
Giardia duodenalis is an enteric parasite commonly detected in children. Exposure to this
organism may lead to asymptomatic or symptomatic infection. Additionally, early-life …
organism may lead to asymptomatic or symptomatic infection. Additionally, early-life …