Background While rotavirus causes severe diarrheal disease in children aged< 5 years,
data on other viral causes in sub-Saharan Africa are limited. Methods In the Vaccine Impact …

Enterotoxigenic E. coli (ETEC) produce heat-labile (LT) and/or heat-stable (ST) enterotoxins,
and commonly cause diarrhea in resource-poor regions. ETEC have been linked repeatedly …

Background: Two of the most important causes of global disease fall in the realm of
environmental health: household air pollution (HAP) and poor water, sanitation, and hygiene …

Background Shigella is the leading bacterial cause of diarrheal mortality in children and can
cause long-term effects on growth and development. No licensed Shigella vaccines …

Background Cryptosporidium is a major pathogen associated with diarrheal disease in
young children. We studied Cryptosporidium diarrhea in children enrolled in the Global …

Background Enterotoxigenic Escherichia coli (ETEC) cause significant diarrheal morbidity
and mortality in children of resource-limited regions, warranting development of effective …

Enterotoxigenic Escherichia coli (ETEC) is an important cause of diarrhea in children in low-
and middle-income countries (LMICs). However, large-scale pathogen burden studies in …

Neonatal diarrhea is one of the most severe diseases in human beings and pigs, leading to
high mortality and growth faltering. Gut microbiome-related studies mostly focus on the …

Background Cryptosporidium is a major cause of diarrheal disease worldwide, including
chronic disease in malnourished children and patients with acquired immune deficiency …

The gram-negative bacterium Shigella is a leading cause of diarrheal morbidity and
mortality in children in low-and middleincome countries. Several promising vaccine …