New insights on bioactivities and biosynthesis of flavonoid glycosides
Flavonoid glycosides are widespread in plants, acting as phytoalexin against biotic stress.
They also have great health benefits to human body. Some of them have been used as …
They also have great health benefits to human body. Some of them have been used as …
Microbial production of natural and non-natural flavonoids: pathway engineering, directed evolution and systems/synthetic biology
In this review, we address recent advances made in pathway engineering, directed
evolution, and systems/synthetic biology approaches employed in the production and …
evolution, and systems/synthetic biology approaches employed in the production and …
Bacterial biosynthesis of flavonoids: Overview, current biotechnology applications, challenges, and prospects
CO Okoye, H Jiang, Y Wu, X Li, L Gao… - Journal of Cellular …, 2023 - Wiley Online Library
Flavonoids are secondary metabolites present in plant organs and tissues. These natural
metabolites are the most prevalent and display a wide range of beneficial physiological …
metabolites are the most prevalent and display a wide range of beneficial physiological …
[HTML][HTML] Glycosyltransferases: Mining, engineering and applications in biosynthesis of glycosylated plant natural products
B He, X Bai, Y Tan, W Xie, Y Feng, GY Yang - Synthetic and Systems …, 2022 - Elsevier
UDP-Glycosyltransferases (UGTs) catalyze the transfer of nucleotide-activated sugars to
specific acceptors, among which the GT1 family enzymes are well-known for their function in …
specific acceptors, among which the GT1 family enzymes are well-known for their function in …
Engineered production of bioactive polyphenolic O-glycosides
Polyphenolic compounds (such as quercetin and resveratrol) possess potential medicinal
values due to their various bioactivities, but poor water solubility hinders their health benefits …
values due to their various bioactivities, but poor water solubility hinders their health benefits …
Flavonoids, terpenoids, and polyketide antibiotics: Role of glycosylation and biocatalytic tactics in engineering glycosylation
UM Vasudevan, EY Lee - Biotechnology advances, 2020 - Elsevier
Flavonoids, terpenoids, and polyketides are structurally diverse secondary metabolites used
widely as pharmaceuticals and nutraceuticals. Most of these molecules exist in nature as …
widely as pharmaceuticals and nutraceuticals. Most of these molecules exist in nature as …
Recent developments in the enzymatic O-glycosylation of flavonoids
B Hofer - Applied microbiology and biotechnology, 2016 - Springer
The glycosylation of bioactive compounds, such as flavonoids, is of particular relevance, as
it modulates many of their pharmacokinetic parameters. This article reviews the literature …
it modulates many of their pharmacokinetic parameters. This article reviews the literature …
Double promoter expression systems for recombinant protein production by industrial microorganisms
Using double promoter expression systems is a promising approach to increase
heterologous protein production. In this review, current double promoter expression systems …
heterologous protein production. In this review, current double promoter expression systems …
Microbial Biosynthesis of Chrysazin Derivatives in Recombinant Escherichia coli and Their Biological Activities
Anthraquinone and its derivatives show remarkable biological properties such as
anticancer, antibacterial, antifungal, and antiviral activities. Hence, anthraquinones …
anticancer, antibacterial, antifungal, and antiviral activities. Hence, anthraquinones …
3-O-Glucosylation of quercetin enhances inhibitory effects on the adipocyte differentiation and lipogenesis
CW Lee, JY Seo, J Lee, JW Choi, S Cho, JY Bae… - Biomedicine & …, 2017 - Elsevier
Glycosylation of natural flavonoids with various sugar moieties can affect their
physicochemical and pharmacological properties. In this study, the plant flavonoids …
physicochemical and pharmacological properties. In this study, the plant flavonoids …