Regiospecific biosynthesis of tamarixetin derivatives in Escherichia coli

P Parajuli, RP Pandey, JK Sohng - Biochemical engineering journal, 2018 - Elsevier
A potential anti-oxidant compound tamarixetin, which can reduce the thiol toxicity, and an
inhibitor of a complex multicasual disease (gastric ulcer) tamarixetin 3-O-β-d-glucoside were …

In vitro single-vessel enzymatic synthesis of novel Resvera-A glucosides

JY Shin, RP Pandey, HY Jung, LL Chu, YI Park… - Carbohydrate …, 2016 - Elsevier
An in vitro enzymatic glycosylation system is developed for the efficient synthesis of
glucosides of 3, 5-dihydroxy-N-(4-hydroxyphenyl) benzamide (resvera-A), a chemically …

[HTML][HTML] Microbial synthesis of non-natural anthraquinone glucosides displaying superior antiproliferative properties

TTH Nguyen, RP Pandey, P Parajuli, JM Han, HJ Jung… - Molecules, 2018 - mdpi.com
Anthraquinones, naturally occurring bioactive compounds, have been reported to exhibit
various biological activities, including anti-inflammatory, antiviral, antimicrobial, and …

Donor substrate flexibility study of AtUGT89C1, a glycosyltransferase from Arabidopsis thaliana

P Parajuli, RP Pandey, S Darsandhari… - Journal of …, 2016 - Taylor & Francis
AtUGT89C1, a glycosyltransferase from Arabidopsis thaliana, has shown interesting
characteristics such as accepting diverse NDP-D/L-sugars as glycosyl donors. Genistein …

Biosynthesis of a novel fisetin glycoside from engineered Escherichia coli

RP Pandey, P Parajuli, LL Chu, SY Kim… - Journal of Industrial and …, 2016 - Elsevier
Abstract Escherichia coli BL21 (DE3)/ΔpgiΔzwfΔgalU mutant was engineered by
overexpressing thymidine diphosphate (dTDP)-d-glucose synthase (tgs), dTDP-d-glucose 4 …

Enzymatic synthesis of novel unnatural phenoxodiol glycosides with a glycosyl donor flexible glycosyltransferase MeUGT1

NJ Lee, Y Kwon, W Kang, M Seo, Y Seol… - Enzyme and Microbial …, 2022 - Elsevier
Isoflavonoids are of great interest due to their human health-promoting properties, which
have resulted in studies on exploiting these phytochemicals as hotspots in diverse bio …

An integrative approach to improving the biocatalytic reactions of whole cells expressing recombinant enzymes

KC Shin, DK Oh - World Journal of Microbiology and Biotechnology, 2021 - Springer
Biotransformation is a selective, stereospecific, efficient, and environment friendly method,
compared to chemical synthesis, and a feasible tool for industrial and pharmaceutical …

[HTML][HTML] Enzymatic synthesis of myricetin 3-O-galactoside through a whole-cell biocatalyst

Z Xu, W He, C Liu, J Kong - Chinese Herbal Medicines, 2020 - Elsevier
Objective Myricetin 3-O-galactoside is an active compound with pharmaceutical potential.
The insufficient supply of this compound becomes a bottleneck in the druggability study of …

Tightly regulated and high level expression vector construction for Escherichia coli BL21 (DE3)

AK Chaudhary, EY Lee - Journal of Industrial and Engineering Chemistry, 2015 - Elsevier
A 474-bp ds-DNA linker-A containing all bio-parts was designed to construct tightly inducible
expression vector, pNB1, for Escherichia coli. The cymR repressor expressed constitutively …

[引用][C] 鼠李糖基转移酶研究进展

闫雅如, 齐博文, 莫婷, 王晓晖, 王娟, 史社坡, 刘晓… - 有机化学, 2018