Treating the Side Effects of Exogenous Glucocorticoids; Can We Separate the Good From the Bad?

R Pofi, G Caratti, DW Ray, JW Tomlinson - Endocrine Reviews, 2023 - academic.oup.com
It is estimated that 2% to 3% of the population are currently prescribed systemic or topical
glucocorticoid treatment. The potent anti-inflammatory action of glucocorticoids to deliver …

[HTML][HTML] Response to biologics and clinical remission in the adult German Asthma Net Severe Asthma Registry Cohort

K Milger, H Suhling, D Skowasch, A Holtdirk… - The Journal of Allergy …, 2023 - Elsevier
Background Recently, criteria for evaluation of response to biologics have been proposed
and the concept of clinical remission has gained attention as a possible goal even in severe …

Cardiovascular diseases or type 2 diabetes mellitus and chronic airway diseases: mutual pharmacological interferences

M Cazzola, P Rogliani, J Ora… - … in Chronic Disease, 2023 - journals.sagepub.com
Chronic airway diseases (CAD), mainly asthma and chronic obstructive pulmonary disease
(COPD), are frequently associated with different comorbidities. Among them, cardiovascular …

Effects of Fluticasone Propionate on Klebsiella pneumoniae and Gram-Negative Bacteria Associated with Chronic Airway Disease

LA Begley, K Opron, G Bian, AJ Kozik, C Liu, J Felton… - Msphere, 2022 - Am Soc Microbiol
Inhaled corticosteroids (ICS) are commonly prescribed first-line treatments for asthma and
chronic obstructive pulmonary disease (COPD). Recent evidence has shown that ICS use is …

Biomarker-guided withdrawal of inhaled corticosteroids in asthma patients with a non-T2 inflammatory phenotype–a randomized controlled trial study protocol

CH Mosbech, NS Godtfredsen, CS Ulrik… - BMC Pulmonary …, 2023 - Springer
Background Non-T2 asthma is characterized by the absence of elevated type 2 inflammatory
biomarkers such as blood-eosinophils, total and allergen-specific Immunoglobulin E and …

Delivery technology of inhaled therapy for asthma and COPD

MYT Chow, HW Pan, JKW Lam - Advances in Pharmacology, 2023 - Elsevier
Inhaled therapy is the cornerstone of the management of asthma and chronic obstructive
pulmonary disease (COPD). Drugs such as bronchodilators and corticosteroids are …

[HTML][HTML] Inhaled corticosteroids is not associated with the risk of pneumonia in asthma

YJ Lee, YB Park - Tuberculosis and Respiratory Diseases, 2023 - ncbi.nlm.nih.gov
The introduction of inhaled corticosteroids (ICS) for the management of asthma has led to a
decrease in acute exacerbation of asthma. However, there are concerns regarding the …

Impact of Inhaled and Intranasal Corticosteroids Exposure on the Risk of Ocular Hypertension and Glaucoma: A Systematic Review and Meta-Analysis

A Vinokurtseva, M Fung, E Ai Li, R Zhang… - Clinical …, 2022 - Taylor & Francis
Purpose Starting in 2019, the Global Initiative for Asthma recommended the use of inhaled
corticosteroids (ICS) as part of reliever combination therapy in patients 12 years of age and …

Nanoparticles of Lactiplantibacillus plantarum K8 Reduce Staphylococcus aureus Respiratory Infection and Tumor Necrosis Factor Alpha- and Interferon Gamma …

J Hong, M Son, J Sin, H Kim, DK Chung - Nutrients, 2023 - mdpi.com
Multiple studies have confirmed that Lactiplantibacillus plantarum has beneficial effects in
respiratory diseases, including respiratory tract infections, asthma, and chronic obstructive …

Unripe Rubus occidentalis, Ellagic Acid, and Urolithin A Attenuate Inflammatory Responses in IL-1β-Stimulated A549 Cells and PMA-Stimulated Differentiated HL-60 …

S Kim, J Kim, Y Song, S Kim, H Kong - Nutrients, 2023 - mdpi.com
Unripe Rubus occidentalis (uRO) contains various natural polyphenols with beneficial
physiological activities and is particularly rich in ellagic acid (EA). EA has ameliorated type 2 …