Cancer-associated venous thromboembolism
AA Khorana, N Mackman, A Falanga… - Nature reviews Disease …, 2022 - nature.com
Cancer-associated thrombosis (including venous thromboembolism (VTE) and arterial
events) is highly consequential for patients with cancer and is associated with worsened …
events) is highly consequential for patients with cancer and is associated with worsened …
Neutrophil extracellular traps: villains and targets in arterial, venous, and cancer-associated thrombosis
Recent studies have demonstrated a role of neutrophils in both venous and arterial
thrombosis. A key prothrombotic feature of neutrophils is their ability to release web-like …
thrombosis. A key prothrombotic feature of neutrophils is their ability to release web-like …
Arterial events, venous thromboembolism, thrombocytopenia, and bleeding after vaccination with Oxford-AstraZeneca ChAdOx1-S in Denmark and Norway …
Objective To assess rates of cardiovascular and haemostatic events in the first 28 days after
vaccination with the Oxford-AstraZeneca vaccine ChAdOx1-S in Denmark and Norway and …
vaccination with the Oxford-AstraZeneca vaccine ChAdOx1-S in Denmark and Norway and …
Thrombus structural composition in cardiovascular disease
Thrombosis is a major complication of cardiovascular disease, leading to myocardial
infarction, acute ischemic stroke, or venous thromboembolism. Thrombosis occurs when a …
infarction, acute ischemic stroke, or venous thromboembolism. Thrombosis occurs when a …
Inflammation, infection and venous thromboembolism
ME Colling, BE Tourdot, Y Kanthi - Circulation research, 2021 - Am Heart Assoc
The association between inflammation, infection, and venous thrombosis has long been
recognized; yet, only in the last decades have we begun to understand the mechanisms …
recognized; yet, only in the last decades have we begun to understand the mechanisms …
Therapeutic strategies for thrombosis: new targets and approaches
N Mackman, W Bergmeier, GA Stouffer… - Nature reviews Drug …, 2020 - nature.com
Antiplatelet agents and anticoagulants are a mainstay for the prevention and treatment of
thrombosis. However, despite advances in antithrombotic therapy, a fundamental challenge …
thrombosis. However, despite advances in antithrombotic therapy, a fundamental challenge …
Fibrinogen and fibrin in hemostasis and thrombosis
S Kattula, JR Byrnes, AS Wolberg - … , thrombosis, and vascular …, 2017 - Am Heart Assoc
Multiple mechanisms mediate thrombin generation and consequently the thrombin
concentration present during fibrin formation. First, the levels of pro-and anticoagulants …
concentration present during fibrin formation. First, the levels of pro-and anticoagulants …
Cryo-shocked platelet coupled with ROS-responsive nanomedicine for targeted treatment of thromboembolic disease
Thrombolysis with tissue plasminogen activator (tPA) provides the most common therapy for
ischemic stroke onset within the past 4.5 h. However, enhanced neutrophil infiltration and …
ischemic stroke onset within the past 4.5 h. However, enhanced neutrophil infiltration and …
Platelet GPVI (glycoprotein VI) and thrombotic complications in the venous system
The immunoglobulin receptor GPVI (glycoprotein VI) is selectively expressed on
megakaryocytes and platelets and is currently recognized as a receptor for not only collagen …
megakaryocytes and platelets and is currently recognized as a receptor for not only collagen …
Elaborately engineering a self‐Indicating dual‐drug nanoassembly for site‐specific photothermal‐potentiated thrombus penetration and thrombolysis
Z Zhao, X Zhang, H Zhang, X Shan, M Bai… - Advanced …, 2022 - Wiley Online Library
Thrombotic cardio‐cerebrovascular diseases seriously threaten human health. Currently,
conventional thrombolytic treatments are challenged by the low utilization, inferior thrombus …
conventional thrombolytic treatments are challenged by the low utilization, inferior thrombus …