With their ever-growing prevalence, obesity and diabetes represent major health threats of
our society. Based on estimations by the World Health Organization, approximately 300 …

Endocannabinoids acting via CB 1 receptors (CB 1 R) play a critical role in regulating
energy homeostasis, which was the rationale for the pharmaceutical development of CB 1 R …

The endocannabinoid system (ECS) is composed of the endocannabinoid ligands
anandamide (AEA) and 2-arachidonoylgycerol (2-AG), their target cannabinoid receptors …

Endocannabinoid signalling is considered one of the most important modulatory systems in
a whole organism. Research has yielded great insight on the mechanisms that link …

The endocannabinoid (eCB) system is widely expressed in many central and peripheral
tissues, and is involved in a plethora of physiological processes. Among these, activity of the …

Gut-brain signaling controls food intake and energy homeostasis, and its activity is thought
to be dysregulated in obesity. We will explore new studies that suggest the …

The endocannabinoid system (ECS) consists of endogenous cannabinoids, their receptors,
and metabolic enzymes that play a critical homeostatic role in modulating polyunsaturated …

There is growing evidence that glucose metabolism in the liver is in part under the control of
the endocannabinoid system (ECS) which is also supported by its presence in this organ …

Thanks to the success of modern antiretroviral therapy (ART), people living with HIV (PLWH)
have life expectancies which approach that of persons in the general population. However …

Despite numerous prevention methodologies and treatment options, hepatocellular
carcinoma (HCC) still remains as the third leading life-threatening cancer. It is thus pertinent …