Exposome in ischaemic heart disease: beyond traditional risk factors

RA Montone, M Camilli, C Calvieri… - European Heart …, 2024 - academic.oup.com
Ischaemic heart disease represents the leading cause of morbidity and mortality, typically
induced by the detrimental effects of risk factors on the cardiovascular system. Although …

A review of air pollution as a driver of cardiovascular disease risk across the diabetes spectrum

LJ Bonanni, S Wittkopp, C Long, JO Aleman… - Frontiers in …, 2024 - frontiersin.org
The prevalence of diabetes is estimated to reach almost 630 million cases worldwide by the
year 2045; of current and projected cases, over 90% are type 2 diabetes. Air pollution …

Proteomic analysis reveals activation of platelet- and fibrosis-related pathways in hearts of ApoE−/− mice exposed to diesel exhaust particles

I Jung, YJ Cho, M Park, K Park, SH Lee, WH Kim… - Scientific Reports, 2023 - nature.com
Air pollution is an environmental risk factor linked to multiple human diseases including
cardiovascular diseases (CVDs). While particulate matter (PM) emitted by diesel exhaust …

Modulatory effects of dietary saturated fatty acids on platelet mitochondrial function following short-term exposure to ambient Particulate Matter (PM2.5)

W Shen, H Chen, C Shih, J Samet… - Journal of Toxicology and …, 2024 - Taylor & Francis
Exposure to ambient fine particulate matter (PM2. 5) was found to produce vascular injury,
possibly by activating platelets within days after exposure. The aim of this study was to …

Ethanol Extracts from the Aerial Parts of Inula japonica and Potentilla chinensis Alleviate Airway Inflammation in Mice That Inhaled Particulate Matter 10 and Diesel …

SH Jung, KS Chung, CS Na, HS Ahn, YK Shin, KT Lee - Nutrients, 2023 - mdpi.com
Air pollution causes various airway diseases. However, many commonly used treatments
can have high risks of side effects or are costly. To examine the anti-inflammatory properties …

USFDA-approved parenteral peptide formulations and excipients: Industrial perspective

S Kumar, SN Sanap, M Vasoya, M Handa… - Journal of Drug Delivery …, 2024 - Elsevier
Parenteral preparations are sterile and non-pyrogenic formulations designed for delivery
into the human or animal body by injection, infusion, or implantation. Peptides are widely …

Joint Exposure to Ambient Air Pollutants, Genetic Risk, and Ischemic Stroke: A Prospective Analysis in UK Biobank

P Li, Y Wang, D Tian, M Liu, X Zhu, Y Wang, C Huang… - Stroke, 2024 - Am Heart Assoc
BACKGROUND: Our primary objective was to assess the association between joint
exposure to various air pollutants and the risk of ischemic stroke (IS) and the modification of …

Palliative effects of carnosol on lung‐deposited pollutant particles‐induced thrombogenicity and vascular injury in mice

S Beegam, NE Zaaba, O Elzaki… - Pharmacology …, 2024 - Wiley Online Library
The toxicity of inhaled particulate air pollution perseveres even at lower concentrations than
those of the existing air quality limit. Therefore, the identification of safe and effective …

The effects of ambient particulate matter air pollution on platelets and hemostasis

S Hantrakool, M Sriwichai… - Frontiers in Public …, 2024 - frontiersin.org
Introduction Elevated ambient pollution exposure is potentially linked to thromboembolism.
However, the mechanisms by which particulate matter (PM) interferes with the balance of …

Streptinone, a New Indanone Derivative from a Marine-Derived Streptomyces massiliensis, Inhibits Particulate Matter-Induced Inflammation

HS Lee, DP Nagahawatta, YJ Jeon, MA Lee, CS Heo… - Marine Drugs, 2023 - mdpi.com
Inflammatory diseases caused by air pollution, especially from particulate matter (PM)
exposure, have increased daily. Accordingly, attention to treatment or prevention for these …