[HTML][HTML] Therapeutic effects of green tea polyphenol (‒)-Epigallocatechin-3-Gallate (EGCG) in relation to molecular pathways controlling inflammation, oxidative stress …

D Mokra, M Joskova, J Mokry - International journal of molecular sciences, 2022 - mdpi.com
(‒)-Epigallocatechin-3-gallate (EGCG) is the most abundant polyphenol in green tea.
Thanks to multiple interactions with cell surface receptors, intracellular signaling pathways …

[HTML][HTML] Therapeutic targeting of NF-κB in acute lung injury: a double-edged sword

MW Millar, F Fazal, A Rahman - Cells, 2022 - mdpi.com
Acute lung injury/acute respiratory distress syndrome (ALI/ARDS) is a devastating disease
that can be caused by a variety of conditions including pneumonia, sepsis, trauma, and most …

[HTML][HTML] Green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG): a time for a new player in the treatment of respiratory diseases?

D Mokra, J Adamcakova, J Mokry - Antioxidants, 2022 - mdpi.com
(-)-Epigallocatechin-3-gallate (EGCG) is a major polyphenol of green tea that possesses a
wide variety of actions. EGCG acts as a strong antioxidant which effectively scavenges …

[HTML][HTML] A targeted metabolomics approach for sepsis-induced ARDS and its subphenotypes

Y Chang, HJ Yoo, SJ Kim, K Lee, CM Lim, SB Hong… - Critical Care, 2023 - Springer
Background Acute respiratory distress syndrome (ARDS) is etiologically and clinically a
heterogeneous disease. Its diagnostic characteristics and subtype classification, and the …

[HTML][HTML] Acute endotoxemia-induced respiratory and intestinal dysbiosis

E Goossens, J Li, C Callens… - International Journal of …, 2022 - mdpi.com
Systemic inflammatory response syndrome (SIRS) is a severe condition characterized by
systemic inflammation, which may lead to multiple organ failure, shock and death. SIRS is …

Effect fraction of Bletilla striata (Thunb.) Reichb. f. alleviates LPS-induced acute lung injury by inhibiting p47phox/NOX2 and promoting the Nrf2/HO-1 signaling …

F Jiang, C Hua, J Pan, S Peng, D Ning, C Chen, S Li… - Phytomedicine, 2024 - Elsevier
Abstract Background & Aims The effect fraction of Bletilla striata (Thunb.) Reichb. f.(EFBS), a
phenolic-rich extract, has significant protective effects on lipopolysaccharide (LPS)-induced …

Growth hormone–releasing hormone in endothelial inflammation

N Barabutis, MS Akhter, KT Kubra, K Jackson - Endocrinology, 2023 - academic.oup.com
The discovery of hypothalamic hormones propelled exciting advances in pharmacotherapy
and improved life quality worldwide. Growth hormone–releasing hormone (GHRH) is a …

[HTML][HTML] Differential pattern of cell death and ROS production in human airway epithelial cells exposed to quinones combined with Heated-PM2. 5 and/or Asian sand …

A Honda, K Inoue, M Higashihara, T Ichinose… - International Journal of …, 2023 - mdpi.com
The combined toxicological effects of airborne particulate matter (PM), such as PM2. 5, and
Asian sand dust (ASD), with surrounding chemicals, particularly quinones, on human airway …

[HTML][HTML] Ribociclib leverages phosphodiesterase 4 inhibition in the treatment of neutrophilic inflammation and acute respiratory distress syndrome

PJ Chen, SH Chen, YL Chen, YH Wang, CY Lin… - Journal of Advanced …, 2024 - Elsevier
Introduction Overwhelming neutrophil activation and oxidative stress significantly contribute
to acute respiratory distress syndrome (ARDS) pathogenesis. However, the potential of …

[HTML][HTML] Effects of hyperoxia and hyperoxic oscillations on the proteome of murine lung microvascular endothelium

A Tiboldi, E Hunyadi-Gulyas, P Wohlrab, JA Schmid… - Antioxidants, 2022 - mdpi.com
Patients presenting with insufficient tissue oxygenation and impaired lung function as in
acute respiratory distress syndrome (ARDS) frequently require mechanical ventilation with …