Background Colorectal cancer (CRC) is one of the most common malignant tumors of the
digestive tract. According to the research of circular RNAs in the CRC field, compared with …

COL1A1 is an important extracellular matrix component that is associated with poor
prognosis in cancers. In this study, As1411 aptamer-conjugated liposomes were used for …

Objective This study aims at exploring the relationship between necroptosis-related miRNAs
and colon cancer prognosis. Methods We downloaded the miRNA sequencing data from the …

Traditional cancer treatments have posed numerous obstacles, including toxicity, multiple
drug resistance, and financial cost. On the contrary, bioactive phytochemicals used in …

Background and aim Cancer stem cells (CSCs) are essential challenge in recurrence-free
treatment of colorectal cancer (CRC) Patients. Targeting CSCs related genes can provide …

Purpose Colorectal cancer (CRC) remains the third most common tumor worldwide.
Ulcerative colitis (UC) could cause chronic inflammation and ulcers in the colon and rectum …

In this study, epithelial cell adhesion molecule (EpCAM) aptamer-activated nanoparticles
(Ap-NPs) were synthesised to enhance treatment efficiency in colorectal cancer (CRC) …

Background Treatment of locally advanced HPV-negative head and neck squamous cell
carcinoma (HNSCC) with photon radiation is the standard of care but shows only moderate …

Neoadjuvant chemoradiation (nCRT) followed by radical surgery is the preferred option for
locally advanced colorectal cancer (CRC) treatment. However, chemo/radio-resistance …

In this work, a tumor-targeting liposome containing anti-nucleolin aptamer AS1411 (Apt-Lip-
GEF) was developed to deliver gefitinib (GEF) for the treatment of colon cancer. The …