[HTML][HTML] A single, extinction-based treatment with a kappa opioid receptor agonist elicits a long-term reduction in cocaine relapse
JA Heinsbroek, AB Furbish, J Peters - Neuropsychopharmacology, 2018 - nature.com
Kappa opioid receptor (KOR) agonists have known anti-addiction properties and can reduce
drug seeking. Their potential for clinical use has largely been daunted by their aversive …
drug seeking. Their potential for clinical use has largely been daunted by their aversive …
[HTML][HTML] Kappa Opioid Receptors in Mesolimbic Terminals Mediate Escalation of Cocaine Consumption
L Gordon-Fennell, RD Farero, LM Burgeno, NL Murray… - bioRxiv, 2023 - ncbi.nlm.nih.gov
Increases in drug consumption over time, also known as escalation, is a key behavioral
component of substance use disorder (SUD) that is related to potential harm to users, such …
component of substance use disorder (SUD) that is related to potential harm to users, such …
[HTML][HTML] Research advances in treatment of neurological and psychological diseases by acupuncture at the Acupuncture Meridian Science Research Center
B Lee, SN Kim, HJ Park, H Lee - Integrative Medicine Research, 2014 - Elsevier
Acupuncture is an ancient therapeutic intervention that can be traced back at least 2100
years and is emerging worldwide as one of the most widely used therapies in the field of …
years and is emerging worldwide as one of the most widely used therapies in the field of …
The Effect of Dezocine on the Median Effective Dose of Sufentanil-Induced Respiratory Depression in Patients Undergoing Spinal Anesthesia Combined with Low …
YK Gui, XH Zeng, R Xiao, WF Xi, D Zhang… - Drug Design …, 2023 - Taylor & Francis
Purpose The application of sedation and analgesia in spinal anesthesia has many benefits,
but the risk of respiratory depression (RD) caused by opioids cannot be ignored. We aimed …
but the risk of respiratory depression (RD) caused by opioids cannot be ignored. We aimed …
Induction of depressive‐like effects by subchronic exposure to cocaine or heroin in laboratory rats
The effect of psychoactive drugs on depression has usually been studied in cases of
prolonged drug addiction and/or withdrawal, without much emphasis on the effects of …
prolonged drug addiction and/or withdrawal, without much emphasis on the effects of …
Repeated stress exposure causes strain‐dependent shifts in the behavioral economics of cocaine in rats
PA Groblewski, C Zietz, I Willuhn, PEM Phillips… - Addiction …, 2015 - Wiley Online Library
Cocaine‐experienced W istar and W istar K yoto (WKY) rats received four daily repeated
forced swim stress sessions (R‐FSS), each of which preceded 4‐hour cocaine self …
forced swim stress sessions (R‐FSS), each of which preceded 4‐hour cocaine self …
The nociceptin receptor as an emerging molecular target for cocaine addiction
K Lutfy, NT Zaveri - Progress in molecular biology and translational …, 2016 - Elsevier
Cocaine addiction is a global public health and socioeconomic issue that requires
pharmacological and cognitive therapies. Currently there are no FDA-approved medications …
pharmacological and cognitive therapies. Currently there are no FDA-approved medications …
[HTML][HTML] Psychiatric neural networks and neuropharmacology: Selected advances and novel implications
A Ghanemi - Saudi Pharmaceutical Journal, 2014 - Elsevier
Psychiatric disorders are often considered as simple imbalances between a limited number
of cerebral neurotransmitters. In fact, it is more complicated than this “simple approach” and …
of cerebral neurotransmitters. In fact, it is more complicated than this “simple approach” and …
Synthesis and pharmacological evaluation of aminothiazolomorphinans at the mu and kappa opioid receptors
BA Provencher, AW Sromek, W Li… - Journal of medicinal …, 2013 - ACS Publications
Previous studies with aminothiazolomorphinans suggested that this class of opioid ligands
may be useful as a potential pharmacotherapeutic to decrease drug abuse. Novel …
may be useful as a potential pharmacotherapeutic to decrease drug abuse. Novel …
A critical role for the melanocortin 4 receptor in stress‐induced relapse to nicotine seeking in rats
X Qi, H Yamada, LW Corrie, Y Ji, RM Bauzo… - Addiction …, 2015 - Wiley Online Library
Tobacco addiction is characterized by a lack of control over smoking and relapse after
periods of abstinence. Smoking cessation leads to a dysphoric state that contributes to …
periods of abstinence. Smoking cessation leads to a dysphoric state that contributes to …