[PDF][PDF] Projection-based reduced order models for parameterized nonlinear time-dependent problems arising in cardiac mechanics
The numerical simulation of several virtual scenarios arising in cardiac mechanics poses a
computational challenge that can be alleviated if traditional full-order models (FOMs) are …
computational challenge that can be alleviated if traditional full-order models (FOMs) are …
[HTML][HTML] The role of computational methods in cardiovascular medicine: a narrative review
Methods We developed computational models of the physical processes encompassed by
the heart function (electrophysiology, electrical activation, force generation, mechanics …
the heart function (electrophysiology, electrical activation, force generation, mechanics …
An integrated heart–torso electromechanical model for the simulation of electrophysiological outputs accounting for myocardial deformation
When generating in-silico clinical electrophysiological outputs, such as electrocardiograms
(ECGs) and body surface potential maps (BSPMs), mathematical models have relied on …
(ECGs) and body surface potential maps (BSPMs), mathematical models have relied on …
Digital twinning of cardiac electrophysiology for congenital heart disease
In recent years, blending mechanistic knowledge with machine learning has had a major
impact in digital healthcare. In this work, we introduce a computational pipeline to build …
impact in digital healthcare. In this work, we introduce a computational pipeline to build …
Computational fluid–structure interaction study of a new wave membrane blood pump
M Martinolli, F Cornat, C Vergara - Cardiovascular Engineering and …, 2022 - Springer
Purpose Wave membrane blood pumps (WMBP) are novel pump designs in which blood is
propelled by means of wave propagation by an undulating membrane. In this paper, we …
propelled by means of wave propagation by an undulating membrane. In this paper, we …
Modelling and simulation for preclinical cardiac safety assessment of drugs with human iPSC-derived cardiomyocytes
P Kügler - Jahresbericht der Deutschen Mathematiker …, 2020 - Springer
As a potentially life threatening side effect, pharmaceutical compounds may trigger cardiac
arrhythmias by impeding the heart's electrical and mechanical function. For this reason, any …
arrhythmias by impeding the heart's electrical and mechanical function. For this reason, any …
A non-conforming-in-space numerical framework for realistic cardiac electrophysiological outputs
Computer-based simulations of non-invasive cardiac electrophysiological outputs, such as
electrocardiograms and body surface potential maps, usually entail severe computational …
electrocardiograms and body surface potential maps, usually entail severe computational …
On the stability of a loosely-coupled scheme based on a Robin interface condition for fluid-structure interaction
We consider a loosely-coupled algorithm for fluid-structure interaction based on a Robin
interface condition for the fluid problem (explicit Robin-Neumann scheme). We study the …
interface condition for the fluid problem (explicit Robin-Neumann scheme). We study the …
An oscillation-free fully partitioned scheme for the numerical modeling of cardiac active mechanics
F Regazzoni, A Quarteroni - arXiv preprint arXiv:2007.15714, 2020 - arxiv.org
In silico models of cardiac electromechanics couple together mathematical models
describing different physics. One instance is represented by the model describing the …
describing different physics. One instance is represented by the model describing the …
Electrogram fractionation during sinus rhythm occurs in normal voltage atrial tissue in patients with atrial fibrillation
Introduction Electrogram (EGM) fractionation is often associated with diseased atrial tissue;
however, mechanisms for fractionation occurring above an established threshold of 0.5 mV …
however, mechanisms for fractionation occurring above an established threshold of 0.5 mV …