To explore the role of genetic factors in the pathogenesis of hypertension, our study
investigated the gender-specific association between four polymorphisms in the Apelin/APJ …

Background and objective: Incidences of hypertension are increasing and this condition is
more common in men than in women. We selected six well-characterized polymorphisms …

Hypertension (HT) has recently been defined as a systolic blood pressure (BP) of≥ 130 mm
Hg and/or a diastolic BP of≥ 80 mm Hg. It is important to further understand the …

Background and Aims The genes encoding adipose-derived hormone leptin and its receptor
(LEPR) are increasingly deemed as hypertension-susceptibility genes. In this meta-analysis …

Background The variant rs9943582 of APLNR (apelin receptor) was identified by a large-
scale study to be associated with an increased risk of ischemic stroke in a Japanese …

The aim of this study was to evaluate if polymorphisms of APLN and APLNR genes may play
a role as susceptibility markers for hypertension in a group of Mexican-Mestizo patients. A …

Objectives: Apelin-APJ system has been implicated in the regulation of metabolic
homeostasis. This study aimed to explore the genetic predisposition of the apelin-APJ …

In this study, we sought to examine the association between 10 genetic variants in the matrix
metalloproteinase (MMP) family genes and the risk of hypertension among northeastern …

Introduction: Apelin plays an important part in regulating blood pressure, metabolism, and
the development of cancer. Recent studies have investigated the association of apelin …

L'apéline, un peptide d'origine neuro-endocrine, et son récepteur (Apéline-R) sont co-
localisés avec l'arginine-vasopressine (AVP) dans les neurones magnocellulaires …