Computational fluid dynamics (CFD) is an important tool for the simulation of the
cardiovascular function and dysfunction. Due to the complexity of the anatomy, the …

We introduce a multiphysics and geometric multiscale computational model, suitable to
describe the hemodynamics of the whole human heart, driven by a four-chamber …

The complexity of cardiac electrophysiology, involving dynamic changes in numerous
components across multiple spatial (from ion channel to organ) and temporal (from …

Background Simulating the cardiac function requires the numerical solution of multi-physics
and multi-scale mathematical models. This underscores the need for streamlined, accurate …

A major challenge in the computational fluid dynamics modeling of the heart function is the
simulation of isovolumetric phases when the hemodynamics problem is driven by a …

Cardiac mechanics models are developed to represent a high level of detail, including
refined anatomies, accurate cell mechanics models, and platforms to link microscale …

Sufficient myocardial perfusion plays a pivotal role in maintaining normal pump function.
However the development of a comprehensive myocardial perfusion model remains …

Stroke is a leading cause of death and disability worldwide. Atrial myopathy, including
fibrosis, is associated with an increased risk of ischemic stroke, but the mechanisms …

Purpose: accurate modeling of blood dynamics in the coronary microcirculation is a crucial
step towards the clinical application of in silico methods for the diagnosis of coronary artery …

Práce se zabývá matematickým modelováním situací vznikajících při vyšetření perfuze
myokardu pomocí vpuštění kontrastní látky (KL). Popis transportu a přestupu KL z cévního …