Replacement of the furanosyl oxygen with a methylene unit in the ribose sugar in
nucleosides 1 and nucleotides 2 prompted the rise of a new nucleoside class with very …

Typical nucleosides are initially obtained from the nucleic acids, DNA and RNA, by
enzymatic hydrolysis, and they are of great biological importance in metabolic pathways. 1 …

BACKGROUND Nucleoside and nucleotide analogs have long been used as
pharmaceutical ingredients against a variety of viruses and cancers. Currently, a number of …

BACKGROUND Nucleoside and nucleotide analogs have long been used as
pharmaceutical ingredients against a variety of viruses and cancers. Currently, a number of …

Conformationally restricted, orthogonally protected 2, 4-diaminocarboxylates with a
cyclopentane skeleton were efficiently synthesized from β-lactam 6, the syntheses involving …

1-α-O-Methyl-3-O, 5-O-TIPDS-arabinose was converted, in multiple steps, to 2, 6-dioxa-
bicyclo [3, 2, 1] octane derivatives, which were condensed with silylated nucleoside bases to …

Three stereoisomers of a wax ester meromycolate have been prepared starting from
mannitol. A detailed comparison of their NMR spectra with those reported for a homologous …

A stereselective synthesis of 3-oxabicyclo [3.2. 0] heptane nucleoside analogues, which
were designed as conformational mimics of the anti-HIV agents 2 ', 3 '-didehydro-2 ', 3 ' …

(11R, 12S)-Lactobacillic acid has been prepared from 2, 3-O-isopropylidene-d-
glyceraldehyde, in a sequence involving asymmetric cyclopropanation, and from cis …

d-and l-2 ', 3 '-dideoxy-2 ', 3 '-endo-methylene nucleosides were synthesized as potential
antiviral agents. The key intermediates 5-O-tert-butyldiphenylsilyl-d-and l-2, 3-dideoxy-2, 3 …