Stem cell therapy in heart diseases–cell types, mechanisms and improvement strategies
P Müller, H Lemcke, R David - Cellular Physiology and Biochemistry, 2018 - karger.com
A large number of clinical trials have shown stem cell therapy to be a promising therapeutic
approach for the treatment of cardiovascular diseases. Since the first transplantation into …
approach for the treatment of cardiovascular diseases. Since the first transplantation into …
[HTML][HTML] Stem cell-derived exosome in cardiovascular diseases: macro roles of micro particles
Y Yuan, W Du, J Liu, W Ma, L Zhang, Z Du… - Frontiers in …, 2018 - frontiersin.org
The stem cell-based therapy has emerged as the promising therapeutic strategies for
cardiovascular diseases (CVDs). Recently, increasing evidence suggest stem cell-derived …
cardiovascular diseases (CVDs). Recently, increasing evidence suggest stem cell-derived …
N-cadherin overexpression mobilizes the protective effects of mesenchymal stromal cells against ischemic heart injury through a β-catenin–dependent manner
W Yan, C Lin, Y Guo, Y Chen, Y Du, WB Lau… - Circulation …, 2020 - Am Heart Assoc
Rationale: Mesenchymal stromal cell–based therapy is promising against ischemic heart
failure. However, its efficacy is limited due to low cell retention and poor paracrine function …
failure. However, its efficacy is limited due to low cell retention and poor paracrine function …
[HTML][HTML] New approaches for enhancement of the efficacy of mesenchymal stem cell-derived exosomes in cardiovascular diseases
L Ahmed, K Al-Massri - Tissue Engineering and Regenerative Medicine, 2022 - Springer
Cardiovascular diseases (CVDs) remain a major health concern worldwide, where
mesenchymal stem cells (MSCs) therapy gives great promise in their management through …
mesenchymal stem cells (MSCs) therapy gives great promise in their management through …
[HTML][HTML] Human Stem Cells for Cardiac Disease Modeling and Preclinical and Clinical Applications—Are We on the Road to Success?
CD Correia, A Ferreira, MT Fernandes, BM Silva… - Cells, 2023 - mdpi.com
Cardiovascular diseases (CVDs) are pointed out by the World Health Organization (WHO)
as the leading cause of death, contributing to a significant and growing global health and …
as the leading cause of death, contributing to a significant and growing global health and …
Mesenchymal stem cell transplantation for ischemic diseases: mechanisms and challenges
TT Van Nguyen, NB Vu, P Van Pham - Tissue Engineering and …, 2021 - Springer
Ischemic diseases are conditions associated with the restriction or blockage of blood supply
to specific tissues. These conditions can cause moderate to severe complications in …
to specific tissues. These conditions can cause moderate to severe complications in …
[HTML][HTML] Mesenchymal stem cells in systemic sclerosis: allogenic or autologous approaches for therapeutic use?
P Rozier, A Maria, R Goulabchand… - Frontiers in …, 2018 - frontiersin.org
Systemic sclerosis (SSc) is a rare autoimmune disease, which is potentially lethal. The
physiopathology of the disease is still incompletely elucidated although the role of …
physiopathology of the disease is still incompletely elucidated although the role of …
Elabela gene therapy promotes angiogenesis after myocardial infarction
L Jin, Y Pan, Q Li, J Li, Z Wang - Journal of cellular and …, 2021 - Wiley Online Library
This study was aimed at investigating whether Elabela (ELA) gene therapy can promote
angiogenesis in the treatment of myocardial infarction (MI). The fusion expression plasmid …
angiogenesis in the treatment of myocardial infarction (MI). The fusion expression plasmid …
MHY2233 Attenuates Replicative Cellular Senescence in Human Endothelial Progenitor Cells via SIRT1 Signaling
S Lamichane, SH Baek, YJ Kim, JH Park… - Oxidative medicine …, 2019 - Wiley Online Library
Cardiovascular diseases (CVDs) are a major cause of death worldwide. Due to the
prevalence of many side effects and incomplete recovery from pharmacotherapies, stem cell …
prevalence of many side effects and incomplete recovery from pharmacotherapies, stem cell …
Systemic and local delivery of mesenchymal stem cells for heart renovation: Challenges and innovations
In the beginning stage of heart disease, the blockage of blood flow frequently occurs due to
the persistent damage and even death of myocardium. Cicatricial tissue developed after the …
the persistent damage and even death of myocardium. Cicatricial tissue developed after the …