[HTML][HTML] Small intestinal phosphate absorption: novel therapeutic implications
J Yee, D Rosenbaum, JW Jacobs… - American Journal of …, 2021 - karger.com
Background: Chronic kidney disease (CKD) affects approximately 15% of adults in the USA.
As CKD progresses, urinary phosphate excretion decreases and results in phosphate …
As CKD progresses, urinary phosphate excretion decreases and results in phosphate …
Progress in pharmacotherapy for the treatment of hyperphosphatemia in renal failure
V Cernaro, E Longhitano, V Calabrese… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Among the clinical and metabolic complications of progressive chronic kidney
disease (CKD), CKD-mineral bone disorder (CKD-MBD) significantly contributes to morbidity …
disease (CKD), CKD-mineral bone disorder (CKD-MBD) significantly contributes to morbidity …
Safety and efficacy of tenapanor for long-term serum phosphate control in maintenance dialysis: a 52-week randomized phase 3 trial (PHREEDOM)
Background Treating hyperphosphatemia is a tenet of dialysis care. This trial assessed the
safety and efficacy of tenapanor for the management of hyperphosphatemia. Methods In this …
safety and efficacy of tenapanor for the management of hyperphosphatemia. Methods In this …
Enhanced phosphate absorption in intestinal epithelial cell‐specific NHE3 knockout mice
Aims The kidneys play a major role in maintaining Pi homeostasis. Patients in later stages of
CKD develop hyperphosphatemia. One novel treatment option is tenapanor, an intestinal …
CKD develop hyperphosphatemia. One novel treatment option is tenapanor, an intestinal …
[HTML][HTML] Constipation in Patients With Chronic Kidney Disease
RR Cha, SY Park, M Camilleri - … of Neurogastroenterology and …, 2023 - ncbi.nlm.nih.gov
Constipation is a frequent symptom in patients with chronic kidney disease (CKD). This
review outlines the mechanisms and management of constipation in patients with CKD from …
review outlines the mechanisms and management of constipation in patients with CKD from …
Intestinal phosphorus absorption: recent findings in translational and clinical research
KMH Gallant, CJ Vorland - Current opinion in nephrology and …, 2021 - journals.lww.com
Intestinal phosphorus absorption: recent findings in transla... : Current Opinion in Nephrology
and Hypertension Intestinal phosphorus absorption: recent findings in translational and clinical …
and Hypertension Intestinal phosphorus absorption: recent findings in translational and clinical …
Tenapanor: A new treatment option for hyperphosphatemia in end stage kidney disease
T Lin, A Al-Makki, B Shepler - Journal of Pharmacy & …, 2022 - journals.library.ualberta.ca
Purpose: This narrative review explores the currently published studies that have evaluated
tenapanor for the treatment of hyperphosphatemia in end-stage kidney disease (ESKD) …
tenapanor for the treatment of hyperphosphatemia in end-stage kidney disease (ESKD) …
Tenapanor-A Novel Approach for Management of Hyperphosphatemia in End Stage Renal Disease: A Clinical Study Aggregate Review
L Lobo, N Kishore, M Sharma - Journal of Drug Delivery and …, 2024 - jddtonline.info
The critical importance of phosphate regulation in chronic kidney disease (CKD) has been
well understood for decades. But new findings, frequently applicable to routine medical care …
well understood for decades. But new findings, frequently applicable to routine medical care …
Physiological regulation of phosphate homeostasis
J Marks, RJ Unwin - Vitamins and Hormones, 2022 - Elsevier
Phosphate homeostasis is dependent on the interaction and coordination of four main organ
systems: thyroid/parathyroids, gastrointestinal tract, bone and kidneys, and three key …
systems: thyroid/parathyroids, gastrointestinal tract, bone and kidneys, and three key …
[PDF][PDF] Tenapanor Improves Long-Term Control of Hyperphosphatemia in Patients Receiving Maintenance Dialysis: the NORMALIZE Study
AL Silva, GM Chertow, GT Hernandez, RI Lynn… - Kidney360, 2023 - journals.lww.com
Background: Most patients with end-stage kidney disease and hyperphosphatemia have
difficulty controlling serum phosphate concentrations (sP) despite maintenance dialysis …
difficulty controlling serum phosphate concentrations (sP) despite maintenance dialysis …