Over 20 million Americans are affected with asthma. Many will require some type of surgical
procedure during which their asthma management should be optimized. Preoperative …

High-mobility group box chromosomal protein 1 (HMGB-1) has recently been shown as an
important late mediator of endotoxin shock, intra-abdominal sepsis, and acute lung injury …

Background Eight clinical trials involving the administration of preoperative iv
methylprednisolone have been undertaken in order to decrease the considerable …

Purpose The aim of this retrospective study was to evaluate whether minimally invasive
esophagectomy (MIE) in the prone position has advantages over the left decubitus position …

Background The aim of this study was to investigate the prognostic impact of postoperative
systemic inflammation in patients with stage I gastric cancer. Methods This study reviewed …

Background Serum C-reactive protein (CRP) is an acute-phase protein, synthesized during
any proinflammatory response in the body. Preoperative elevation of serum CRP has been …

Summary Sivelestat sodium hydrate (Ono Pharmaceutical Co., Osaka, Japan) is a selective
inhibitor of neutrophil elastase (NE) and is effective in reducing acute lung injury associated …

PURPOSE: This study was designed to assess whether preoperative, short-term,
intravenously administered high doses of methylprednisolone (30 mg/kg 90 minutes before …

Objectives: Cytokines and chemokines potentially modulate postoperative immune
response. Association of circulating cytokines and chemokines with postoperative infectious …

Severe injury and infection are associated with autonomic dysfunction. The realization that a
dysregulation in autonomic function may predispose a host to excessive inflammatory …