Few fungi are pathogenic to humans. Of these, Cryptococcus neoformans has emerged as
an important cause of mortality in immunocompromised patients, especially those with AIDS …

Enzymes play key roles in fungal pathogenesis. Manipulation of enzyme expression or
activity can significantly alter the infection process, and enzyme expression profiles can be a …

The mechanisms by which macromolecules are transported through the cell wall of fungi are
not known. A central question in the biology of Cryptococcus neoformans, the causative …

Cryptococcus neoformans and distantly related fungal species release extracellular vesicles
that traverse the cell wall and contain a varied assortment of components, some of which …

The human fungal pathogen Cryptococcus neoformans is able to rapidly and effectively
adapt to varying conditions, favoring its survival in the environment and in the infected host …

Cryptococcus neoformans is an encapsulated yeast that is pathogenic for humans. The
capsule is a major virulence factor composed mainly of glucuronoxylomannan (GXM) and …

Cryptococcus neoformans is a fungal pathogen responsible for cryptococcosis and
cryptococcal meningitis. The C. neoformans capsular polysaccharide and shed …

ABSTRACT A major ceramide monohexoside (CMH) was purified from lipidic extracts of
Cryptococcus neoformans. This molecule was analyzed by high-performance thin-layer …

UDP-xylose is a sugar donor required for the synthesis of diverse and important glycan
structures in animals, plants, fungi, and bacteria. Xylose-containing glycans are particularly …

Inhalation of Cryptococcus into the respiratory system is the main route of acquisition of
human infection, yet pulmonary cryptococcosis goes mostly unrecognized by many …