Hepatitis C virus has been identified a quarter of a decade ago as a leading cause of
chronic viral hepatitis that can lead to cirrhosis and hepatocellular carcinoma. Only a …

There have been unprecedented advances in the identification of new treatment targets for
chronic hepatitis B that are being developed with the goal of achieving functional cure in …

Natural killer (NK) cells are important in protection against virus infections, and many viruses
have evolved mechanisms to thwart NK cell activity. NK cells respond to inflammatory …

Objective In order to refine new therapeutic strategies in the pipeline for HBV cure,
evaluation of virological and immunological changes compartmentalised at the site of …

In order to optimally refine the multiple emerging drug targets for hepatitis B virus (HBV), it is
vital to evaluate virological and immunological changes at the site of infection. Traditionally …

Patients infected with the hepatitis C virus (HCV) are characterized by a high incidence of
chronic infection, which results in chronic hepatitis, liver cirrhosis, and hepatocellular …

NK cells are important antiviral effectors, highly enriched in the liver, with the potential to
regulate immunopathogenesis in persistent viral infections. Here we examined whether …

Introduction Murine hepatic NK cells exhibit adaptive features, with liver‐specific adhesion
molecules CXCR6 and CD49a acting as surface markers. Methods We investigated human …

Clinical infection with hantaviruses cause two severe acute diseases, hemorrhagic fever
with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). These diseases …

Background & Aims Natural killer (NK) cells are known to exert strong antiviral activity. Killer
cell lectin-like receptor subfamily G member 1 (KLRG1) is expressed by terminally …