Magnesium (Mg) is involved in the regulation of metabolism and in the maintenance of the
homeostasis of all the tissues, including the brain, where it harmonizes nerve signal …

Synapse dysfunction and loss are hallmarks of neurodegenerative diseases that correlate
with cognitive decline. However, the mechanisms and therapeutic strategies to prevent or …

Psychedelic drugs have reemerged as tools to treat several brain disorders. Cultural
attitudes toward them are changing, and scientists are once again investigating the neural …

Background Gut homeostasis, including intestinal immunity and microbiome, is essential for
cognitive function via the gut-brain axis. This axis is altered in high-fat diet (HFD)-induced …

Excitation–transcription coupling (E–TC) links synaptic and cellular activity to nuclear gene
transcription. It is generally accepted that E–TC makes a crucial contribution to learning and …

As one of most common and severe mental disorders, major depressive disorder (MDD)
significantly increases the risks of premature death and other medical conditions for patients …

Neurodegenerative diseases and depression are multifactorial disorders with a complex
and poorly understood physiopathology. Astrocytes play a key role in the functioning of …

Neurotrophins are a family of secreted proteins expressed in the peripheral nervous system
and the central nervous system that support neuronal survival, synaptic plasticity, and …

Extracellular vesicles (EVs) have emerged as mediators of cellular communication, in part
via the delivery of associated microRNAs (miRNAs), small non-coding RNAs that regulate …

Extracellular vesicles (EVs) play an important role in intercellular communication as carriers
of signalling molecules such as bioactive miRNAs, proteins and lipids. EVs are key players …