Long-chain non-coding RNAs (lncRNAs) are RNA molecules with a length greater than 200
nt and no function of encoding proteins. lncRNAs play a precise regulatory function at …

DNA replication timing and three-dimensional (3D) genome organization are associated
with distinct epigenome patterns across large domains. However, whether alterations in the …

Although general anesthetics have been used in the clinic for more than 170 years, the ways
in which they induce amnesia, unconsciousness, analgesia, and immobility remain elusive …

Chemotherapy is a commonly utilized treatment strategy for colon cancer, a prevalent
malignancy. The study intends to probe the function and mechanism of protocadherin 7 …

Metastasis and chemoresistance are the leading causes of death in patients with
hepatocellular carcinoma (HCC). microRNAs (miRNAs or miRs) may be useful as …

Background Lung cancer is one of the most malignant tumors. However, neither the
pathogenesis of lung cancer nor the prognosis markers are completely clear. The purpose of …

Introduction Colon adenocarcinoma (COAD) is the third most common tumor of the digestive
tract. Recent studies reported that lncRNA's abnormal expression might play a vital role in …

Chronic myeloid leukemia (CML) is a hematological disease, and imatinib (IM) resistance
represents a major problem for its clinical treatment. In the present study, the role of tribbles …

Background AU-rich elements (ARE) are vital cis-acting short sequences in the 3'UTR
affecting mRNA stability and translation. The deregulation of ARE-mediated pathways can …

DNA replication timing and three-dimensional (3D) genome organisation occur across large
domains associated with distinct epigenome patterns to functionally compartmentalise …