Staphylococcus aureus Toxins: An Update on Their Pathogenic Properties and Potential Treatments

N Ahmad-Mansour, P Loubet, C Pouget… - Toxins, 2021 - mdpi.com
Staphylococcus aureus is a clinically important pathogen that causes a wide range of
human infections, from minor skin infections to severe tissue infection and sepsis. S. aureus …

[HTML][HTML] Staphylococcus aureus vaccine research and development: the past, present and future, including novel therapeutic strategies

J Clegg, E Soldaini, RM McLoughlin… - Frontiers in …, 2021 - frontiersin.org
Staphylococcus aureus is one of the most important human pathogens worldwide. Its high
antibiotic resistance profile reinforces the need for new interventions like vaccines in …

Adult chronic rhinosinusitis

C Bachert, B Marple, RJ Schlosser, C Hopkins… - Nature reviews Disease …, 2020 - nature.com
Chronic rhinosinusitis (CRS) occurs in> 10% of the adult population in Europe and the USA
and can be differentiated into CRS without nasal polyps and CRS with nasal polyps …

Staphylococcus aureus and its IgE-inducing enterotoxins in asthma: current knowledge

C Bachert, M Humbert, NA Hanania… - European …, 2020 - Eur Respiratory Soc
While immunoglobulin (Ig) E is a prominent biomarker for early-onset, its levels are often
elevated in non-allergic late-onset asthma. However, the pattern of IgE expression in the …

Engineering aluminum hydroxyphosphate nanoparticles with well-controlled surface property to enhance humoral immune responses as vaccine adjuvants

Z Liang, Y Yang, G Yu, H Zhu, X Xia, C Chen, D Fu… - Biomaterials, 2021 - Elsevier
Aluminum phosphate adjuvants play a critical role in human inactivated and subunit
prophylactic vaccines. However, a major challenge is that the underlying mechanism of …

Staphylococcus aureus vaccine preclinical and clinical development: current state of the art

D Redi, C SPERTILLI RAFFAELLI… - NEW …, 2018 - usiena-air.unisi.it
Staphylococcus aureus is a major pathogen in both community and hospital settings. It is a
significant etiological agent to treat in healthcare-related infections due to both its ability to …

Contribution of Staphylococcal Enterotoxin B to Staphylococcus aureus Systemic Infection

JS Bae, F Da, R Liu, L He, H Lv… - The Journal of …, 2021 - academic.oup.com
Staphylococcal enterotoxin B (SEB), which is produced by the major human pathogen,
Staphylococcus aureus, represents a powerful superantigenic toxin and is considered a …

Rapid and Broad Immune Efficacy of a Recombinant Five-Antigen Vaccine against Staphylococcus aureus Infection in Animal Models

H Zeng, F Yang, Q Feng, J Zhang, J Gu, H Jing, C Cai… - Vaccines, 2020 - mdpi.com
Staphylococcus aureus (S. aureus) is a leading cause of both healthcare-and community-
associated infections globally, which result in severe disease and readily developing …

Epidemiological and Clinical Evidence for the Role of Toxins in S. aureus Human Disease

MR Bennett, IP Thomsen - Toxins, 2020 - mdpi.com
Staphylococcus aureus asymptomatically colonizes approximately 30–50% of the
population and is a leading cause of bacteremia, bone/joint infections, and skin infections in …

Anti-virulence compounds against Staphylococcus aureus associated with bovine mastitis: A new therapeutic option?

YNV Sabino, PD Cotter, HC Mantovani - Microbiological Research, 2023 - Elsevier
Bovine mastitis represents a major economic burden faced by the dairy industry. S. aureus is
an important and prevalent bovine mastitis-associated pathogen in dairy farms worldwide …