Treatment of infections caused by extended-spectrum-beta-lactamase-, AmpC-, and carbapenemase-producing Enterobacteriaceae

J Rodríguez-Baño, B Gutiérrez-Gutiérrez… - Clinical microbiology …, 2018 - Am Soc Microbiol
Therapy of invasive infections due to multidrug-resistant Enterobacteriaceae (MDR-E) is
challenging, and some of the few active drugs are not available in many countries. For …

Extended-spectrum β-lactamase-producing Enterobacteriaceae: update on molecular epidemiology and treatment options

G Peirano, JDD Pitout - Drugs, 2019 - Springer
Extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae are a major global
public health concern. Presently, Escherichia coli with CTX-Ms are the most common …

Effect of piperacillin-tazobactam vs meropenem on 30-day mortality for patients with E coli or Klebsiella pneumoniae bloodstream infection and ceftriaxone resistance …

PNA Harris, PA Tambyah, DC Lye, Y Mo, TH Lee… - Jama, 2018 - jamanetwork.com
Importance Extended-spectrum β-lactamases mediate resistance to third-generation
cephalosporins (eg, ceftriaxone) inEscherichia coliandKlebsiella pneumoniae. Significant …

[HTML][HTML] Effect and safety of meropenem–vaborbactam versus best-available therapy in patients with carbapenem-resistant Enterobacteriaceae infections: the TANGO …

RG Wunderink, EJ Giamarellos-Bourboulis… - Infectious diseases and …, 2018 - Springer
Methods A total of 77 patients with confirmed/suspected CRE infection (bacteremia, hospital-
acquired/ventilator-associated bacterial pneumonia, complicated intra-abdominal infection …

[HTML][HTML] Attributable sources of community-acquired carriage of Escherichia coli containing β-lactam antibiotic resistance genes: a population-based modelling study

L Mughini-Gras, A Dorado-García… - The Lancet Planetary …, 2019 - thelancet.com
Background Extended-spectrum β-lactamase-producing Escherichia coli (ESBL-EC),
plasmid-mediated AmpC-producing E coli (pAmpC-EC), and other bacteria are resistant to …

Global antibiotic consumption 2000 to 2010: an analysis of national pharmaceutical sales data

TP Van Boeckel, S Gandra, A Ashok… - The Lancet infectious …, 2014 - thelancet.com
Background Antibiotic drug consumption is a major driver of antibiotic resistance. Variations
in antibiotic resistance across countries are attributable, in part, to different volumes and …

Antibiotic treatment and appendectomy for uncomplicated acute appendicitis in adults and children: a systematic review and meta-analysis

M Podda, C Gerardi, N Cillara, N Fearnhead… - Annals of …, 2019 - journals.lww.com
Objective: The aim of this meta-analysis was to summarize the current available evidence on
nonoperative management (NOM) with antibiotics for uncomplicated appendicitis, both in …

The role of epidemic resistance plasmids and international high-risk clones in the spread of multidrug-resistant Enterobacteriaceae

AJ Mathers, G Peirano, JDD Pitout - Clinical microbiology reviews, 2015 - Am Soc Microbiol
Escherichia coli sequence type 131 (ST131) and Klebsiella pneumoniae ST258 emerged in
the 2000s as important human pathogens, have spread extensively throughout the world …

[HTML][HTML] Antibiotic resistance and extended spectrum beta-lactamases: Types, epidemiology and treatment

S Shaikh, J Fatima, S Shakil, SMD Rizvi… - Saudi journal of …, 2015 - Elsevier
Antibiotic resistance is a problem of deep scientific concern both in hospital and community
settings. Rapid detection in clinical laboratories is essential for the judicious recognition of …

[HTML][HTML] Systematic review and meta-analysis of mortality of patients infected with carbapenem-resistant Klebsiella pneumoniae

L Xu, X Sun, X Ma - Annals of clinical microbiology and antimicrobials, 2017 - Springer
Purpose Carbapenem resistant K. pneumoniae (CRKP) has aroused widespread attention
owing to its very limited therapeutic options, and this strain has increased rapidly in recent …