Osteoporotic fractures and vertebral body reshaping in children with glucocorticoid-treated rheumatic disorders

LM Ward, J Ma, ME Robinson… - The Journal of …, 2021 - academic.oup.com
Context Osteoporotic fractures are an important cause of morbidity in children with
glucocorticoid-treated rheumatic disorders. Objective This work aims to evaluate the …

Neural EGFL like 1 as a potential pro-chondrogenic, anti-inflammatory dual-functional disease-modifying osteoarthritis drug

C Li, Z Zheng, P Ha, W Jiang, EA Berthiaume, S Lee… - Biomaterials, 2020 - Elsevier
Arthritis, an inflammatory condition that causes pain and cartilage destruction in joints,
affects over 54.4 million people in the US alone. Here, for the first time, we demonstrated the …

[HTML][HTML] Clinical practice guidelines for optimizing bone health in Korean children and adolescents

YA Lee, A Kwon, JH Kim, HK Nam, JH Yoo… - Annals of Pediatric …, 2022 - ncbi.nlm.nih.gov
Abstract The Committee on Pediatric Bone Health of the Korean Society of Pediatric
Endocrinology has newly developed evidence-based clinical practice guidelines for …

Nutritional recommendations for patients undergoing prolonged glucocorticoid therapy

GP Esteves, BC Mazzolani, FI Smaira… - … Advances in Practice, 2022 - academic.oup.com
Glucocorticoid (GC) therapy is a common treatment used in rheumatic and autoimmune
diseases, owing to its anti-inflammatory and immunosuppressive effects. However, GC …

Long non‐coding RNA telomerase RNA elements improve glucocorticoid‐induced osteoporosis by EZH2 to regulate DKK1

H Hu, X Guo, T Mu, H Song - International Journal of …, 2023 - Wiley Online Library
Background Glucocorticoid‐induced osteoporosis is the most common secondary cause of
osteoporosis, which increases the risk of fracture. Long non‐coding RNA telomerase RNA …

Tanshinol alleviates microcirculation disturbance and impaired bone formation by attenuating TXNIP signaling in GIO rats

W Lai, Y Mo, D Wang, Y Zhong, L Lu, J Wang… - Frontiers in …, 2021 - frontiersin.org
Impaired bone formation is the main characteristics of glucocorticoid (GC)-induced
osteoporosis (GIO), which can be ameliorated by tanshinol, an aqueous polyphenol isolated …

The molecular etiology and treatment of glucocorticoid-induced osteoporosis

CH Peng, WY Lin, KT Yeh, H Chen, WT Wu… - Tzu Chi Medical …, 2021 - journals.lww.com
Glucocorticoid-induced osteoporosis (GIOP) is the most common form of secondary
osteoporosis, accounting for 20% of osteoporosis diagnoses. Using glucocorticoids for> 6 …

Glucocorticoid-induced osteoporosis: an overview with focus on its prevention and management

E Anastasilaki, J Paccou, K Gkastaris, AD Anastasilakis - Hormones, 2023 - Springer
The widespread use of glucocorticoids (GCs) contributes to the effective management of
several diseases and conditions. However, it comes at a price in the case of the bones …

Parathyroid hormone and bone mineral density: a Mendelian randomization study

Z Qu, F Yang, J Hong, W Wang… - The Journal of Clinical …, 2020 - academic.oup.com
Purpose Accumulating evidence implicates parathyroid hormone (PTH) in the development
of osteoporosis. However, the causal effect of PTH on bone mineral density (BMD) remains …

Associations of abdominal obesity with different types of bone fractures in adults: A systematic review and dose-response meta-analysis of prospective cohort studies

H Zahedi, F Atayie, F Samii Kondrud… - Critical Reviews in …, 2023 - Taylor & Francis
Findings on the association between abdominal obesity and hip fracture were summarized
in a meta-analysis in 2017; however, no study has examined the dose-response association …