[HTML][HTML] Overexpressed SIRT6 ameliorates doxorubicin-induced cardiotoxicity and potentiates the therapeutic efficacy through metabolic remodeling

K Peng, C Zeng, Y Gao, B Liu, L Li, K Xu, Y Yin… - … Pharmaceutica Sinica B, 2023 - Elsevier
Since the utilization of anthracyclines in cancer therapy, severe cardiotoxicity has become a
major obstacle. The major challenge in treating cancer patients with anthracyclines is …

Compound SJ-12 attenuates streptozocin-induced diabetic cardiomyopathy by stabilizing SERCA2a

S Lou, W Zhu, T Yu, Q Zhang, M Wang, L Jin… - … et Biophysica Acta (BBA …, 2024 - Elsevier
Heart failure (HF) is one of the major causes of death among diabetic patients. Although
studies have shown that curcumin analog C66 can remarkably relieve diabetes-associated …

[HTML][HTML] Circular RNA circNEURL4 inhibits cell proliferation and invasion of papillary thyroid carcinoma by sponging miR-1278 and regulating LATS1 expression

W Ding, Y Shi, H Zhang - American Journal of Translational …, 2021 - ncbi.nlm.nih.gov
Circular RNAs (circRNA) are found to be closely associated with cancers as their possibility
as “sponges” to miRNAs, thus liberating the downstream target mRNA. However, deep …

[HTML][HTML] Luminescence of carbon quantum dots and their application in biochemistry

H Bao, Y Liu, H Li, W Qi, K Sun - Heliyon, 2023 - cell.com
Similar to fullerenes, carbon nanotubes and graphene, carbon dots (CDs) are causing a lot
of research work in their own right. CDs are a type of surface-passivated quantum dot that …

[HTML][HTML] IGF2BP2-m6A-circMMP9 axis recruits ETS1 to promote TRIM59 transcription in laryngeal squamous cell carcinoma

J Li, H Cao, J Yang, B Wang - Scientific Reports, 2024 - nature.com
Laryngeal squamous cell carcinoma (LSCC) is a common malignancy of the head and neck.
Recently, circular RNA (circRNA) has been studied extensively in multisystem diseases …

[HTML][HTML] A new FGF1 variant protects against adriamycin-induced cardiotoxicity via modulating p53 activity

M Xiao, Y Tang, G Lu, J Niu, J Li, Q Liu, Z Wang… - Redox Biology, 2022 - Elsevier
A cumulative and progressively developing cardiomyopathy induced by adriamycin (ADR)-
based chemotherapy is a major obstacle for its clinical application. However, there is a lack …

Inhibition of sepsis‐induced acute kidney injury via the circITCH‐miR‐579‐3p‐ZEB2 axis

Q Li, T Wang, X Wang, XY Ge, T Yang… - Environmental …, 2023 - Wiley Online Library
Circular RNAs (circRNAs) are linked to the regulation of sepsis‐induced acute kidney injury
(AKI). However, the function of circITCH in the development of sepsis‐induced AKI is still …

[HTML][HTML] Tripartite motif 25 ameliorates doxorubicin-induced cardiotoxicity by degrading p85α

Y Shen, H Zhang, Y Ni, X Wang, Y Chen, J Chen… - Cell Death & …, 2022 - nature.com
Doxorubicin (DOX)-based chemotherapy is widely used to treat malignant tumors; however,
the cardiotoxicity induced by DOX restricts its clinical usage. A therapeutic dose of DOX can …

[HTML][HTML] A narrative review of circular RNAs as potential biomarkers and therapeutic targets for cardiovascular diseases

C Liu, N Li, G Dai, O Cavdar, H Fang - Annals of Translational …, 2021 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs), a novel class of non-coding RNA, are produced by back-splicing
and were initially considered to be by-products of splicing. In recent years, computational …

Genetic Susceptibility and Mechanisms Underlying the Pathogenesis of Anthracycline‐Associated Cardiotoxicity

Y Ding, K Du, YJ Niu, Y Wang… - Oxidative Medicine and …, 2022 - Wiley Online Library
Anthracyclines are chemotherapeutic agents widely used to treat a variety of cancers, and
these drugs have revolutionized our management of cancer patients. The dose‐dependent …