N-Acetyl-Aspartyl-Glutamate in Brain Health and Disease

C Morland, K Nordengen - International Journal of Molecular Sciences, 2022 - mdpi.com
N-acetyl-aspartyl-glutamate (NAAG) is the most abundant dipeptide in the brain, where it
acts as a neuromodulator of glutamatergic synapses by activating presynaptic metabotropic …

Magnetic resonance spectroscopy of traumatic brain injury and subconcussive hits: A systematic review and meta–analysis

JM Joyce, PL La, R Walker, AD Harris - Journal of Neurotrauma, 2022 - liebertpub.com
Magnetic resonance spectroscopy (MRS) is a non-invasive technique used to study
metabolites in the brain. MRS findings in traumatic brain injury (TBI) and subconcussive hit …

Brain metabolites measured with magnetic resonance spectroscopy in pediatric concussion and orthopedic injury: An Advancing Concussion Assessment in …

PL La, JM Joyce, TK Bell, M Mauthner… - Human Brain …, 2023 - Wiley Online Library
Millions of children sustain a concussion annually. Concussion disrupts cellular signaling
and neural pathways within the brain but the resulting metabolic disruptions are not well …

Theory and computation of nuclear shielding

T Kupka - 2020 - books.rsc.org
A review of the literature published from January to December 2019 on theoretical aspects
of nuclear magnetic shielding is presented. It covers both non-relativistic and relativistic …

[HTML][HTML] Meta-analysis and open-source database for in vivo brain Magnetic Resonance spectroscopy in health and disease

AT Gudmundson, A Koo, A Virovka, AL Amirault… - Analytical …, 2023 - Elsevier
Abstract Proton (1 H) Magnetic Resonance Spectroscopy (MRS) is a non-invasive tool
capable of quantifying brain metabolite concentrations in vivo. Prioritization of …

Consistency of frontal cortex metabolites quantified by magnetic resonance spectroscopy within overlapping small and large voxels

MM DeMayo, A McGirr, B Selby, FP MacMaster… - Scientific Reports, 2023 - nature.com
Single voxel magnetic resonance spectroscopy (MRS) quantifies metabolites within a
specified volume of interest. MRS voxels are constrained to rectangular prism shapes …

J-difference GABA-edited MRS reveals altered cerebello-thalamo-cortical metabolism in patients with hepatic encephalopathy

HJ Zöllner, TA Thiel, ND Füllenbach, MS Jördens… - Metabolic Brain …, 2023 - Springer
Hepatic encephalopathy (HE) is a common neurological manifestation of liver cirrhosis and
is characterized by an increase of ammonia in the brain accompanied by a disrupted …

Longitudinal changes in brain metabolites following pediatric concussion

PL La, R Walker, TK Bell, W Craig, Q Doan… - Scientific reports, 2024 - nature.com
Concussion is commonly characterized by a cascade of neurometabolic changes following
injury. Magnetic Resonance Spectroscopy (MRS) can be used to quantify neurometabolites …

[HTML][HTML] Metabolite changes and impact factors in mild traumatic brain injury patients: a review on magnetic resonance spectroscopy

S Huang, Y Lyu, T Liu, D Zhu - Meta-Radiology, 2024 - Elsevier
The high incidence of mild traumatic brain injury (mTBI) and the associated post-concussion
symptoms, such as headache and cognitive deficits, have captured the significant attention …

[HTML][HTML] Self-Regulation of Cerebral Metabolism and Its Neuroprotective Effect After Hypoxic-Ischemic Injury: Evidence From 1H-MRS

K Li, Y Zheng, X Wang - Frontiers in Neuroanatomy, 2021 - frontiersin.org
1H-MRS technology can be used to non-invasively detect the content of cerebral
metabolites, to assess the severity of hypoxic-ischemic (HI) injury, and to predict the …