About 70 to 80% of an oral dose of digoxin is absorbed, mainly in the proximal part of the
small intestine. The degree of binding to serum albumin is 20 to 30%. Digoxin is extensively …

OBJECTIVES We compared the effects of five pharmacologic regimens on the circadian
rhythm and exercise-induced changes of ventricular rate (VR) in patients with chronic atrial …

The following summarises the contents of both this review and its predecessor in this journal
(Iisalo, 1977). The two reviews should be read in conjunction with each other. Digoxin is …

The role of digoxin and the new beta adrenergic blocking agent, timolol, in controlling heart
rate at rest and during exercise was investigated in 28 patients with chronic atrial fibrillation …

Although therapeutic and toxic serum concentrations of digoxin have been established,
there is sparse information permitting correlation of drug level with clinical effect. This study …

The efficacy and safety of oral verapamil, 240 mg, with or without digoxin were studied in 52
patients with chronic atrial fibrillation at rest, and during mild and maximal exercise. Twenty …

To study the mechanism of the renal handling of digoxin, simultaneous measurements of
digoxin and inulin clearances were performed in 13 digitalized patients with congestive …

Beta-adrenergic blocking agents are commonly used in combination with digitalis to control
excessive heart rate during exercise in patients with chronic atrial fibrillation. However, little …

Serum digoxin concentrations were measured in 101 outpatients by radioimmunoassay with
radioactive iodine 125 to evaluate factors affecting these concentrations. Patient …

Nadolol, a long-acting beta-adrenergic-blocking agent, was evaluated in 20 patients with
chronic atrial fibrillation by means of a randomized, double-blind, crossover study. Patients …