Personalized Medicine (PM) A Critical Appraisal

ST Raza, S Rizvi, FA Allal Ouhtit… - Precision Medicine and …, 2024 - books.google.com
Personalized medicine, also referred to as precision medicine, deals with a clinical model
that delineates patients into different groups based on their ethnicity, lifestyle, food habits …

The pharmacogenetic road to avoid adverse drug reactions and therapeutic failures in revolving door patients with psychiatric illnesses: focus on the CYP2D6 …

F Panza, M Lozupone, E Stella, G Miscio… - Expert Review of …, 2016 - Taylor & Francis
Introduction: A periodical hospital readmission caused by therapeutic failures (TFs) and a
worsening of clinical symptoms most often linked to adverse drug reactions (ADRs) are …

Genomics in Treatment Development

Y Dwivedi, RC Shelton - Drug Development in Psychiatry, 2023 - Springer
Abstract The Human Genome Project mapped the 3 billion base pairs in the human
genome, which ushered in a new generation of genomically focused treatment …

Unsuspected poor metabolizer phenotypes of fluoxetine in bioavailability/bioequivalence studies from an Indian population perspective

M Kandasamy, K Tripathy, S Ravi… - …, 2010 - thieme-connect.com
Fluoxetine, belonging to the class of selective serotonin uptake inhibitors, has been
extensively used for the treatment of depression and other psychiatry related disorders …

Cytochrome P450 in GtoPdb v. 2023.1

K Burns, NA Helsby - IUPHAR/BPS Guide to Pharmacology CITE, 2023 - journals.ed.ac.uk
The cytochrome P450 enzyme superfamily (CYP), EC 1.14.-.-, are haem-containing
monooxygenases with a vast range of both endogenous and exogenous substrates. These …

CYP2D6 ultra-rapid metabolizer phenotype not associated with attempted suicide in a large sample of psychiatric inpatients

DB Stephens, J De Leon - Pharmacogenomics, 2016 - Taylor & Francis
Aim: Suicide accounts for over 800,000 deaths per year worldwide and is the tenth-leading
cause of mortality in USA. Several studies have investigated cytochrome P450 CYP2D6 …

[引用][C] 美托洛尔抗高血压效应个体差异影响因素的研究进展

张晶晶, 缪丽燕 - 中国临床药理学杂志, 2012

Eating disorder symptoms and CYP2D6 variation in Cuban healthy females: a report from the Ibero-American Network of Pharmacogenetics

EM Penas-LLedo, I González, P Dorado… - Current …, 2012 - ingentaconnect.com
CYP2D6 is involved in the metabolism of antidepressants drugs and of the endogenous
neurotransmitter serotonin. We have previously shown an increased number of CYP2D6 …

CYP2D6 Genetic Polymorphism and Psychiatry Patients' Hospitalization Period

EM Peñas-LLedó, A LLerena - Biomarkers in Medicine, 2013 - Taylor & Francis
Full article: CYP2D6 Genetic Polymorphism and Psychiatry Patients' Hospitalization Period Skip
to Main Content Taylor and Francis Online homepage Taylor and Francis Online homepage …

[PDF][PDF] OCT1-mediated cellular drug uptake and interactions between drug transport and drug metabolism

AR Saadatmand - 2012 - core.ac.uk
This research project would not have been possible without the support, patience and
guidance of many people. It is to them that I owe my deepest gratitude. I would like to …