[HTML][HTML] Flux balance analysis-based metabolic modeling of microbial secondary metabolism: current status and outlook

S Qiu, A Yang, H Zeng - PLoS Computational Biology, 2023 - journals.plos.org
In microorganisms, different from primary metabolism for cellular growth, secondary
metabolism is for ecological interactions and stress responses and an important source of …

[HTML][HTML] Step-by-Step Metagenomics for Food Microbiome Analysis: A Detailed Review

J Sadurski, M Polak-Berecka, A Staniszewski, A Waśko - Foods, 2024 - mdpi.com
This review article offers a comprehensive overview of the current understanding of using
metagenomic tools in food microbiome research. It covers the scientific foundation and …

DLTKcat: deep learning-based prediction of temperature-dependent enzyme turnover rates

S Qiu, S Zhao, A Yang - Briefings in Bioinformatics, 2024 - academic.oup.com
The enzyme turnover rate,, quantifies enzyme kinetics by indicating the maximum efficiency
of enzyme catalysis. Despite its importance, values remain scarce in databases for most …

Towards consolidated bioprocessing of biomass and plastic substrates for semi-synthetic production of bio-poly (ethylene furanoate)(PEF) polymer using omics …

MN Omar, MM Minggu, NAN Muhammad… - Enzyme and Microbial …, 2024 - Elsevier
Abstract Poly (ethylene furanoate)(PEF) plastic is a 100% renewable polyester that is
currently being pursued for commercialization as the next-generation bio-based plastic. This …

[HTML][HTML] Deciphering and designing microbial communities by genome-scale metabolic modelling

S Wu, Z Qu, D Chen, H Wu, Q Caiyin, J Qiao - Computational and Structural …, 2024 - Elsevier
Microbial communities are shaped by the complex interactions among organisms and the
environment. Genome-scale metabolic models (GEMs) can provide deeper insights into the …

Proteome trade-off between primary and secondary metabolism shapes acid stress induced bacterial exopolysaccharide production

S Qiu, A Yang, X Yang, W Li, H Zeng, Y Wang - bioRxiv, 2024 - biorxiv.org
The exopolysaccharide (EPS) produced by Lactiplantibacillus plantarum is a high-value
bioproduct in food and health industries, and its biosynthesis has been found as a …

Global sensitivity analysis for investigation of bacterial physiology in complex media with FBA-PRCC

A Sorokin, I Goryanin - bioRxiv, 2024 - biorxiv.org
In this paper we propose the use of FBA-PRCC approach, which is based on sampling flux
space and global sensitivity analysis (GSA), for analysis of the GEM FBA solution space in …