[HTML][HTML] Changing epidemiology, global trends and implications for outcomes of NAFLD

VWS Wong, M Ekstedt, GLH Wong, H Hagström - Journal of hepatology, 2023 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) has rapidly become the most common liver
disease globally and is currently estimated to affect 38% of the global population. Only a …

Lifestyle interventions in nonalcoholic fatty liver disease

ZM Younossi, S Zelber-Sagi, L Henry… - Nature Reviews …, 2023 - nature.com
Nonalcoholic fatty liver disease (NAFLD) is a dynamic chronic liver disease that develops in
close association with metabolic irregularities. Between 2016 and 2019, the global …

[HTML][HTML] Type 2 diabetes, hepatic decompensation, and hepatocellular carcinoma in patients with non-alcoholic fatty liver disease: an individual participant-level data …

DQ Huang, N Noureddin, V Ajmera… - The Lancet …, 2023 - thelancet.com
Background Data are scarce regarding the development of hepatic decompensation in
patients with non-alcoholic fatty liver disease (NAFLD) with and without type 2 diabetes. We …

[HTML][HTML] High prevalence of NASH and advanced fibrosis in type 2 diabetes: a prospective study of 330 outpatients undergoing liver biopsies for elevated ALT, using a …

L Castera, C Laouenan, A Vallet-Pichard… - Diabetes …, 2023 - Am Diabetes Assoc
OBJECTIVE Most people with type 2 diabetes (T2DM) and nonalcoholic steatohepatitis
(NASH) or advanced fibrosis (AF) remain undiagnosed, resulting in missed opportunities for …

Non-invasive diagnosis and monitoring of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis

MA Tincopa, R Loomba - The Lancet Gastroenterology & Hepatology, 2023 - thelancet.com
Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent form of chronic liver disease
that poses challenges in diagnosis and risk stratification. Non-alcoholic steatohepatitis …

Head-to-head comparison between MEFIB, MAST, and FAST for detecting stage 2 fibrosis or higher among patients with NAFLD

BK Kim, N Tamaki, K Imajo, M Yoneda, N Sutter… - Journal of …, 2022 - Elsevier
Background & Aims Patients with non-alcoholic fatty liver disease (NAFLD) and significant
fibrosis (fibrosis stage≥ 2) are candidates for pharmacological trials. The aim of this study …

Noninvasive assessment of liver fibrosis in NAFLD

AJ Sanyal, L Castera, VWS Wong - Clinical Gastroenterology and …, 2023 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) has emerged as a leading cause of liver-related
morbidity and mortality worldwide, afflicting approximately a billion individuals. NAFLD is a …

Fibrosis progression rate in biopsy-proven nonalcoholic fatty liver disease among people with diabetes versus people without diabetes: a multicenter study

DQ Huang, LA Wilson, C Behling, DE Kleiner… - Gastroenterology, 2023 - Elsevier
Background & Aims There are limited data regarding fibrosis progression in biopsy-proven
nonalcoholic fatty liver disease (NAFLD) in people with type 2 diabetes mellitus (T2DM) …

Diabetes and cirrhosis: current concepts on diagnosis and management

L Castera, K Cusi - Hepatology, 2023 - journals.lww.com
Type 2 diabetes mellitus is often associated with cirrhosis as comorbidities, acute illness,
medications, and other conditions profoundly alter glucose metabolism. Both conditions are …

Liver stiffness thresholds to predict disease progression and clinical outcomes in bridging fibrosis and cirrhosis

R Loomba, DQ Huang, AJ Sanyal, QM Anstee… - Gut, 2023 - gut.bmj.com
Objective In retrospective studies, liver stiffness (LS) by vibration-controlled transient
elastography (VCTE) is associated with the risk of liver decompensation in patients with non …