NASH drug treatment development: challenges and lessons
Non-alcoholic fatty liver disease (NAFLD) has become the most common chronic liver
disease worldwide. Although NAFLD is tightly linked to obesity and type 2 diabetes, this liver …
disease worldwide. Although NAFLD is tightly linked to obesity and type 2 diabetes, this liver …
[HTML][HTML] Noninvasive imaging biomarkers for liver fibrosis in nonalcoholic fatty liver disease: current and future
JH Yu, HA Lee, SU Kim - Clinical and molecular hepatology, 2023 - ncbi.nlm.nih.gov
Nonalcoholic fatty liver disease (NAFLD) is increasingly prevalent worldwide and becoming
a major cause of liver disease-related morbidity and mortality. The presence of liver fibrosis …
a major cause of liver disease-related morbidity and mortality. The presence of liver fibrosis …
[HTML][HTML] A global action agenda for turning the tide on fatty liver disease
Conclusions: This consensus-driven multidisciplinary fatty liver disease action agenda
developed by care providers, clinical researchers, and public health and policy experts …
developed by care providers, clinical researchers, and public health and policy experts …
Risk stratification and early detection biomarkers for precision HCC screening
Hepatocellular carcinoma (HCC) mortality remains high primarily due to late diagnosis as a
consequence of failed early detection. Professional societies recommend semi‐annual HCC …
consequence of failed early detection. Professional societies recommend semi‐annual HCC …
[HTML][HTML] Identification of high-risk subjects in nonalcoholic fatty liver disease
C Stern, L Castera - Clinical and molecular hepatology, 2023 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) is becoming the most common liver disease
worldwide, and its burden is expected to increase due to the growing epidemic of obesity …
worldwide, and its burden is expected to increase due to the growing epidemic of obesity …
A practical use of noninvasive tests in clinical practice to identify high‐risk patients with nonalcoholic steatohepatitis
Z Younossi, N Alkhouri, K Cusi, S Isaacs… - Alimentary …, 2023 - Wiley Online Library
Background Patients with nonalcoholic fatty liver disease (NAFLD) with type 2 diabetes
(T2D) or other components of metabolic syndrome are at high risk for disease progression …
(T2D) or other components of metabolic syndrome are at high risk for disease progression …
Remnant cholesterol has a non-linear association with non-alcoholic fatty liver disease
J Chen, Y Su, X Su, F Luo - Diabetes Research and Clinical Practice, 2023 - Elsevier
Objective We intend to look at the link between remnant cholesterol (RC) and nonalcoholic
fatty liver disease (NAFLD). We hypothesise that there may be a positive and nonlinear …
fatty liver disease (NAFLD). We hypothesise that there may be a positive and nonlinear …
Close association of PFASs exposure with hepatic fibrosis than steatosis: evidences from NHANES 2017–2018
W Cheng, M Li, L Zhang, C Zhou, X Zhang… - Annals of …, 2023 - Taylor & Francis
Multiple animals and in vitro studies have demonstrated that perfluoroalkyl and
polyfluoroalkyl substances (PFASs) exposure causes liver damage associated with fat …
polyfluoroalkyl substances (PFASs) exposure causes liver damage associated with fat …
[PDF][PDF] Liver fibrosis in nonalcoholic fatty liver disease patients: Noninvasive evaluation and correlation with cardiovascular disease and mortality
S Ballestri, A Mantovani, M Di Girolamo… - Metab Target Organ …, 2023 - f.oaes.cc
Liver fibrosis is critical for liver-related outcomes and mortality in chronic liver disease,
irrespective of etiology, including nonalcoholic fatty liver disease (NAFLD). NAFLD has been …
irrespective of etiology, including nonalcoholic fatty liver disease (NAFLD). NAFLD has been …
[HTML][HTML] Development and validation of the nonalcoholic fatty liver disease familial risk score to detect advanced fibrosis: a prospective, multicenter study
DQ Huang, N Ahlholm, PK Luukkonen… - Clinical …, 2024 - Elsevier
Background & Aims Nonalcoholic fatty liver disease (NAFLD)-related fibrosis is heritable, but
it is unclear how family history may be used to identify first-degree relatives with advanced …
it is unclear how family history may be used to identify first-degree relatives with advanced …