Secondary bile acids improve risk prediction for non‐invasive identification of mild liver fibrosis in nonalcoholic fatty liver disease

AN Liu, CF Xu, YR Liu, DQ Sun, L Jiang… - Alimentary …, 2023 - Wiley Online Library
Background Dysregulated bile acid (BA) metabolism has been linked to steatosis,
inflammation, and fibrosis in nonalcoholic fatty liver disease (NAFLD). Aim To determine …

Magnetic resonance elastography-based prediction model for hepatic decompensation in NAFLD: A multicenter cohort study

BK Kim, J Bergstrom, R Loomba, N Tamaki, N Izumi… - Hepatology, 2023 - journals.lww.com
Magnetic resonance elastography-based prediction model for h... : Hepatology Magnetic
resonance elastography-based prediction model for hepatic decompensation in NAFLD: A …

Clinical utility of liver fat quantification for determining cardiovascular disease risk among patients with type 2 diabetes

SZ Kuo, S Cepin, J Bergstrom, H Siddiqi… - Alimentary …, 2023 - Wiley Online Library
Background Nonalcoholic fatty liver disease (NAFLD) and type 2 diabetes mellitus (T2DM)
are independent risk factors for cardiovascular disease (CVD). Aims To examine the clinical …

Understanding the burden of nonalcoholic fatty liver disease: time for action

ZM Younossi, L Henry - Diabetes Spectrum, 2024 - Am Diabetes Assoc
The prevalence of nonalcoholic fatty liver disease (NAFLD) in the United States is 38%,
having increased by 50% within the past 3 decades. The estimated NAFLD prevalence …

[HTML][HTML] Noninvasive assessment of hepatic decompensation

M Thiele, S Johansen, M Israelsen, J Trebicka… - Hepatology, 2023 - journals.lww.com
Noninvasive tests (NITs) are used in all aspects of liver disease management. Their most
prominent break-through since the millennium has been in advancing early detection of liver …

Protection of Liver Functions and Improvement of Kidney Functions by Twelve Weeks Consumption of Cuban Policosanol (Raydel®) with a Decrease of Glycated …

KH Cho, JE Kim, T Komatsu, Y Uehara - Life, 2023 - mdpi.com
Policosanol consumption has been associated with treating blood pressure and
dyslipidemia by increasing the level of high-density lipoproteins-cholesterol (HDL-C) and …

Screening for liver fibrosis: Lessons from colorectal and lung cancer screening

M Thiele, PS Kamath, I Graupera, A Castells… - Nature Reviews …, 2024 - nature.com
Many countries have incorporated population screening programmes for cancer, such as
colorectal and lung cancer, into their health-care systems. Cirrhosis is more prevalent than …

[HTML][HTML] Opportunities and barriers in omics-based biomarker discovery for steatotic liver diseases

M Thiele, IF Villesen, L Niu, S Johansen, K Sulek… - Journal of …, 2024 - Elsevier
The rising prevalence of liver diseases related to obesity and excessive use of alcohol is
fuelling an increasing demand for accurate biomarkers aimed at community screening …

Clinical practice guidelines on hemochromatosis: Asian Pacific Association for the Study of the Liver

DHG Crawford, GA Ramm, KR Bridle, AJ Nicoll… - Hepatology …, 2023 - Springer
Hereditary hemochromatosis is the result of pathogenic variants in multiple genes that can
result in increased body iron stores with excess iron deposited in various organs, including …

Noninvasive tests used in risk stratification of patients with nonalcoholic fatty liver disease

L Henry, KE Eberly, D Shah, A Kumar… - Clinics in Liver …, 2023 - liver.theclinics.com
The most current estimate suggests that in 2019, 38% of the world's adult population had
nonalcoholic fatty liver disease (NAFLD). 1 NAFLD is a complex liver disease that occurs as …