Antibacterial activity of flavonoids and their structure–activity relationship: An update review

F Farhadi, B Khameneh, M Iranshahi… - Phytotherapy …, 2019 - Wiley Online Library
Based on World Health Organization reports, resistance of bacteria to well‐known antibiotics
is a major global health challenge now and in the future. Different strategies have been …

Natural products as a source of Alzheimer's drug leads

P Williams, A Sorribas, MJR Howes - Natural product reports, 2011 - pubs.rsc.org
Covering: up to 2010 This review focuses on recent developments in the use of natural
products as therapeutics for Alzheimer's disease. The compounds span a diverse array of …

Natural AChE inhibitors from plants and their contribution to Alzheimer's disease therapy

AP Murray, MB Faraoni, MJ Castro… - Current …, 2013 - ingentaconnect.com
As acetylcholinesterase (AChE) inhibitors are an important therapeutic strategy in
Alzheimer's disease, efforts are being made in search of new molecules with anti-AChE …

Anti-Alzheimer and antioxidant activities of Coptidis Rhizoma alkaloids

HA Jung, BS Min, T Yokozawa, JH Lee… - Biological and …, 2009 - jstage.jst.go.jp
Coptidis Rhizoma and its isolated alkaloids are reported to possess a variety of activities,
including neuroprotective and antioxidant effects. Thus, the anti-Alzheimer and antioxidant …

Alkaloids as a source of potential anticholinesterase inhibitors for the treatment of Alzheimer's disease

EL Konrath, CS Passos, LC Klein-Júnior… - Journal of Pharmacy …, 2013 - academic.oup.com
Objectives The inhibition of acetylcholinesterase (AChE), the key enzyme in the breakdown
of acetylcholine, is currently the main pharmacological strategy available for Alzheimer's …

[HTML][HTML] Berberine: a potential multipotent natural product to combat Alzheimer's disease

HF Ji, L Shen - Molecules, 2011 - mdpi.com
With the accelerated aging of human society Alzheimer's disease (AD) has become one of
the most threatening diseases in the elderly. However, there is no efficient therapeutic agent …

Palmatine: a review of pharmacological properties and pharmacokinetics

D Tarabasz, W Kukula‐Koch - Phytotherapy research, 2020 - Wiley Online Library
The aim of this review is to collect together the results of the numerous studies over the last
two decades on the pharmacological properties of palmatine published in scientific …

Natural and synthetic α-methylenelactones and α-methylenelactams with anticancer potential

A Janecka, A Wyrębska, K Gach, J Fichna… - Drug Discovery …, 2012 - Elsevier
α-Methylene-γ-and δ-lactones, as well as α-methylene-γ-and δ-lactams, are plant-derived
compounds often used in traditional medicine for the treatment of inflammatory diseases. In …

Biologically active isoquinoline alkaloids with drug-like properties from the genus Corydalis

M Iranshahy, RJ Quinn, M Iranshahi - Rsc Advances, 2014 - pubs.rsc.org
The genus Corydalis (Papaveraceae), comprising more than 400 species in Eurasia and
North America, is a rich source of isoquinoline alkaloids with various biological properties …

[HTML][HTML] Extracts from traditional Chinese medicinal plants inhibit acetylcholinesterase, a known Alzheimer's disease target

D Kaufmann, A Kaur Dogra, A Tahrani, F Herrmann… - Molecules, 2016 - mdpi.com
Inhibition of acetylcholinesterase (AChE) is a common treatment for early stages of the most
general form of dementia, Alzheimer's Disease (AD). In this study, methanol …