Timosaponin AIII, a saponin isolated from Anemarrhena asphodeloides, ameliorates learning and memory deficits in mice

B Lee, K Jung, DH Kim - Pharmacology Biochemistry and Behavior, 2009 - Elsevier
Anemarrhenaasphodeloides Bunge (AA, family Liliaceae), which primarily contains
xantones, such as mangiferin, and steroidal saponins, such as timosaponin AIII and …

Anti-acetylcholinesterase activities of mono-herbal extracts and exhibited synergistic effects of the phytoconstituents: A biochemical and computational study

A Balkrishna, S Pokhrel, M Tomer, S Verma, A Kumar… - Molecules, 2019 - mdpi.com
Alzheimer's disease (AD), a neurodegenerative disease, is the most common form of
dementia. Inhibition of acetylcholinesterase (AChE) is a common strategy for the treatment of …

[HTML][HTML] Neuraminidase inhibitory activities of quaternary isoquinoline alkaloids from Corydalis turtschaninovii rhizome

JH Kim, YB Ryu, WS Lee, YH Kim - Bioorganic & medicinal chemistry, 2014 - Elsevier
Clostridium perfringens is a Gram-positive spore-forming bacterium that causes food
poisoning. The neuraminidase (NA) protein of C. perfringens plays a pivotal role in bacterial …

Alzheimer's disease and age-related memory decline (preclinical)

AV Terry Jr, PM Callahan, B Hall, SJ Webster - … Biochemistry and Behavior, 2011 - Elsevier
An unfortunate result of the rapid rise in geriatric populations worldwide is the increasing
prevalence of age-related cognitive disorders such as Alzheimer's disease (AD). AD is a …

[HTML][HTML] Effect of isoquinoline alkaloids from two Hippeastrum species on in vitro acetylcholinesterase activity

LB Pagliosa, SC Monteiro, KB Silva, JP De Andrade… - Phytomedicine, 2010 - Elsevier
The treatment of neurological disorders and neurodegenerative diseases is related to the
levels of acetylcholine (ACh) through the inhibition of acetylcholinesterase (AChE) …

UHPLC-Q-Orbitrap-MS-Based Metabolomics Reveals Chemical Variations of Two Types of Rhizomes of Polygonatum sibiricum

G Luo, J Lin, W Cheng, Z Liu, T Yu, B Yang - Molecules, 2022 - mdpi.com
The rhizomes of Polygonatum sibiricum are commonly consumed as food and also used as
medicine. However, the metabolic profile of P. sibiricum has not been fully revealed yet …

Stephapierrines A–H, new tetrahydroprotoberberine and aporphine alkaloids from the tubers of Stephania pierrei Diels and their anti-cholinesterase activities

W Chaichompoo, P Rojsitthisak, W Pabuprapap… - RSC …, 2021 - pubs.rsc.org
Eight new alkaloids, which are four new tetrahydroprotoberberine alkaloids, stephapierrines
A–D (1–4), and four new aporphine alkaloids, stephapierrines E–H (5–8), together with …

Antibacterial Activity and Multi-Targeting Mechanism of Dehydrocorydaline From Corydalis turtschaninovii Bess. Against Listeria monocytogenes

G Kim, Y Xu, J Zhang, Z Sui, H Corke - Frontiers in microbiology, 2022 - frontiersin.org
Listeria monocytogenes is a foodborne pathogen, with relatively low incidence but high case-
fatality. Phytochemicals have been recognized as a promising antimicrobial agent as an …

Plant-derived acetylcholinesterase inhibitory alkaloids for the treatment of Alzheimer's disease

S Dall'Acqua - Botanics: Targets and Therapy, 2013 - Taylor & Francis
The inhibition of acetylcholinesterase (AChE) has been one of the most used strategies for
the treatment of Alzheimer's disease (AD). The AChE inhibitors (AChE-I) produce not only …

Nutritional and medicinal plants as potential sources of enzyme inhibitors toward the bioactive functional foods: an updated review

H Saleem, A Yaqub, R Rafique… - Critical reviews in …, 2023 - Taylor & Francis
Enzymes are biologically active complex protein molecules that catalyze most chemical
reactions in living organisms, and their inhibitors accelerate biological processes. This …