The endogenous neurotransmitter acetylcholine (ACh), found in vertebrates, stimulates
cholinergic (muscarinic and nicotinic) receptors to mediate cholinergic neuronal …

In the course of screening plants used in folk medicine as memory enhancers, a 70%
ethanolic extract of Stephania rotunda roots showed significant AChE inhibitory activity …

Dementia is a chronic progressive mental disorder, which adversely affects memory,
thinking, comprehension, calculation and language. Some of the most common dementias …

A series of Lycopodium alkaloids, namely lycosquarosine A (1), acetylaposerratinine (2),
huperzine A (3), huperzine B (4), 8α-hydrophlemariurine B (5), and huperzinine (6), has …

Acetylcholinesterase (AChE) inhibitors increase the availability of acetylcholine in central
cholinergic synapses and are the most promising drugs currently available for the treatment …

Background DA‐9701 is a novel prokinetic agent formulated with Pharbitis Semen and
Corydalis Tuber. This study aimed to evaluate the effect of DA‐9701 on stress‐induced …

Nantenine, as well as a number of flexible analogs, were evaluated for acetylcholinesterase
(AChE) inhibitory activity in microplate spectrophotometric assays based on Ellman's …

The inhibition of acetylcholinesterase (AChE) from decomposing acetylcholine (ACh) is
regarded as a common therapeutic strategy for Alzheimer's disease (AD). Screening AChE …

Abstract Alzheimer's disease (AD), the main dementia type accounting for over 70% of the
entire dementia population, progressive decline in memory and executive function. AD …

The protein lysine methyltransferase G9a, which controls gene expression by epigenetic
regulation of H3K9 methylation, is related to various human diseases, including cancer, drug …