Despite the enormous advances in the development of new drugs, the efficacy of current
antitumor therapies is still quite limited, most likely because of the high degree of cancer …

Abstract Background Poorana Chandrothaya Chenthuram (PCC) is a gold-based Siddha
drug, for treating diverse diseases. Rooted in centuries-old traditional use, Siddha texts …

Six undescribed alkaloids together with 15 known alkaloids were isolated from the aerial
parts of Aconitum carmichaelii. Their structures were elucidated extensively by NMR and …

A biochemometrics strategy combining quantitative determination, bioactivity evaluation,
and relationship analysis was proposed for identification of analgesic components of herbs …

乙酰胆碱酯酶抑制剂是阿尔茨海默病治疗药物的研究热点. 根据类胆碱学说,
乙酰胆碱酯酶抑制剂可提高脑部神经递质乙酰胆碱的水平从而改善阿尔茨海默病患者的胆碱 …

Alzheimer's disease (AD) is an age-related neurodegenerative disease. Extensive in vitro
and in vivo experiments have proved that the decreased activity of the cholinergic neuron is …

Oxaprotoberberinones and 5-oxaprotoberberinium were synthesized as bioisosteres of
protoberberines. 5-Oxaprotoberberinones were prepared by linking phenol with the …

Aconitum L.(Ranunculaceae), annual or perennial herbs, are mainly distributed in the
temperate regions of the northern hemisphere. There are about 300 species all over the …

The Alkaloids, Volume 78 is the latest update in a series that has not only covered the topic
for more than 60 years, but is also touted as the leading book series in the field of alkaloid …

Historically, people who study interactions between plants and herbivores focused on the
ecological costs and benefits of synthesizing secondary metabolites. These compounds …