Polycystic ovary syndrome (PCOS) is the most common gynecological endocrine disease,
involving multiple genes, multiple pathways, and complex hormone secretion processes …

The oocyte is the major determinant of embryo developmental competence in all
mammalian species. Although fundamental advances have been generated in the field of …

The sirtuin family, a group of NAD+-dependent class 3 histone deacetylases (HDACs), was
extensively studied initially as a group of longevity genes that are activated in caloric …

Background Being one of the most prevalent metabolic and endocrine disorders, Polycystic
Ovary Syndrome (PCOS) has been proven to be associated with microRNA-130b-3p (miR …

Polycystic ovary syndrome (PCOS) is a common gynecological disease that causes adverse
effects in women in their reproductive phase. Nonetheless, the molecular mechanisms …

The oocyte and the surrounding cumulus cells (CCs) are deeply linked by a complex
bidirectional cross-talk. In this light, the molecular analysis of the CCs is nowadays …

The success of female reproduction relies on high quality oocytes, which is determined by
well-organized cooperation between granulosa cells (GCs) and oocytes during …

Noncoding RNAs (ncRNAs) are a class of nucleotide sequences that cannot be translated
into peptides. ncRNAs can function post-transcriptionally by splicing complementary …

The mechanism related to ovarian follicular is complex, which has not been fully elucidated.
Abundant reports have confirmed that the ovarian function development is closely related to …

Ovarian aging critically influences reproductive potential, with a marked decrease in oocyte
quality and quantity and an increase in oxidative stress and mitochondrial dysfunction. This …