Image-guided cancer surgery using near-infrared fluorescence

AL Vahrmeijer, M Hutteman, JR Van Der Vorst… - Nature reviews Clinical …, 2013 - nature.com
Paradigm shifts in surgery arise when surgeons are empowered to perform surgery faster,
better and less expensively than current standards. Optical imaging that exploits invisible …

Review on near-infrared heptamethine cyanine dyes as theranostic agents for tumor imaging, targeting, and photodynamic therapy

C Shi, JB Wu, D Pan - Journal of biomedical optics, 2016 - spiedigitallibrary.org
A class of near-infrared fluorescence (NIRF) heptamethine cyanine dyes that are taken up
and accumulated specifically in cancer cells without chemical conjugation have recently …

Cancer-associated secondary lymphoedema

SG Rockson, V Keeley, S Kilbreath, A Szuba… - Nature reviews Disease …, 2019 - nature.com
Lymphoedema is an oedematous condition with a specific and complex tissue biology. In
the clinical context of cancer, the pathogenesis of lymphoedema ensues most typically from …

Recent progress in the treatment and prevention of cancer‐related lymphedema

SF Shaitelman, KD Cromwell… - CA: a cancer journal …, 2015 - Wiley Online Library
Answer questions and earn CME/CNE This article provides an overview of the recent
developments in the diagnosis, treatment, and prevention of cancer‐related lymphedema …

Translation of near-infrared fluorescence imaging technologies: emerging clinical applications

EM Sevick-Muraca - Annual review of medicine, 2012 - annualreviews.org
Technical developments in near-infrared fluorescence (NIRF) imaging and tomography
have enabled recent translation into investigational human studies. Noninvasive imaging of …

A review of performance of near-infrared fluorescence imaging devices used in clinical studies

B Zhu, EM Sevick-Muraca - The British journal of radiology, 2015 - academic.oup.com
Near-infrared fluorescence (NIRF) molecular imaging holds great promise as a new “point-of-
care” medical imaging modality that can potentially provide the sensitivity of nuclear …

New diagnostic modalities in the evaluation of lymphedema

TF O'Donnell Jr, JC Rasmussen… - Journal of Vascular …, 2017 - Elsevier
Objective Currently, lymphedema (LED) is typically diagnosed clinically on the basis of a
patient's history and characteristic physical findings. Whereas the diagnosis of LED is …

Mechanical forces and lymphatic transport

JW Breslin - Microvascular research, 2014 - Elsevier
This review examines the current understanding of how the lymphatic vessel network can
optimize lymph flow in response to various mechanical forces. Lymphatics are organized as …

Fluorescent Nanoprobes Dedicated to in Vivo Imaging: From Preclinical Validations to Clinical Translation

J Mérian, J Gravier, F Navarro, I Texier - Molecules, 2012 - mdpi.com
With the fast development, in the last ten years, of a large choice of set-ups dedicated to
routine in vivo measurements in rodents, fluorescence imaging techniques are becoming …

Targeting lymphatic function as a novel therapeutic intervention for rheumatoid arthritis

EM Bouta, RD Bell, H Rahimi, L Xing… - Nature Reviews …, 2018 - nature.com
Although clinical outcomes for patients with rheumatoid arthritis (RA) have greatly improved
with the use of biologic and conventional DMARDs, approximately 40% of patients do not …