The dentate gyrus (DG) is important for encoding contextual memories, but little is known
about how a population of DG neurons comes to encode and support a particular memory …

In mice, various instinctive behaviors can be triggered by olfactory input. Despite growing
knowledge of the brain regions involved in such behaviors, the organization of the neural …

Zif268 is a transcription regulatory protein, the product of an immediate early gene. Zif268
was originally described as inducible in cell cultures; however, it was later shown to be …

The immediate-early gene Arc is transcribed in neurons that are part of stable neural
networks activated during spatial exploratory behaviors. Arc protein has been demonstrated …

In the 14 years since it was discovered that specific genes could be dynamically regulated in
the brain by neural activity, there has been a substantial research focus attempting to …

The brain stores and recalls memories through a set of neurons, termed engram cells.
However, it is unclear how these cells are organized to constitute a corresponding memory …

Long-term memory and its putative synaptic correlates the late phases of both long-term
potentiation and long-term depression require enhanced protein synthesis. On the basis of …

The neuroanatomical and molecular basis of fear memory retrieval was studied by analyzing
the expression of the plasticity-associated immediate early gene zif268. Cellular quantitative …

There has been nearly a century of interest in the idea that encoding and storage of
information in the brain requires changes in the efficacy of synaptic connections between …

Small untranslated BC1 and BC200 RNAs are translational regulators that are selectively
targeted to somatodendritic domains of neurons. They are thought to operate as modulators …