Real-world data: towards achieving the achievable in cancer care

CM Booth, S Karim, WJ Mackillop - Nature reviews Clinical oncology, 2019 - nature.com
The use of data from the real world to address clinical and policy-relevant questions that
cannot be answered using data from clinical trials is garnering increased interest. Indeed …

[HTML][HTML] Management of elderly patients with NSCLC; updated expert's opinion paper: EORTC Elderly Task Force, Lung Cancer Group and International Society for …

AG Pallis, C Gridelli, U Wedding, C Faivre-Finn… - Annals of oncology, 2014 - Elsevier
Non-small-cell lung cancer (NSCLC) is a very common disease in the elderly population
and its incidence in this particular population is expected to increase further, because of the …

Metformin use and all-cause and prostate cancer–specific mortality among men with diabetes

D Margel, DR Urbach, LL Lipscombe… - Journal of Clinical …, 2013 - ascopubs.org
Purpose To evaluate the association between cumulative duration of metformin use after
prostate cancer (PC) diagnosis and all-cause and PC-specific mortality among patients with …

Association between metformin use and risk of prostate cancer and its grade

D Margel, D Urbach, LL Lipscombe… - Journal of the …, 2013 - academic.oup.com
Background Metformin is commonly prescribed to treat type 2 diabetes. Recent evidence
suggests that it may possess antitumoral properties. The aim of this study was to test the …

[HTML][HTML] Adjuvant chemotherapy of completely resected early stage non-small cell lung cancer (NSCLC)

Y Liang, HA Wakelee - Translational lung cancer research, 2013 - ncbi.nlm.nih.gov
Surgery is regarded as the primary treatment modality for early stage non-small cell lung
cancer (NSCLC), but even after complete resection, a substantial percentage of these …

Older cancer patients and COVID‐19 outbreak: practical considerations and recommendations

A Brunello, A Galiano, S Finotto, S Monfardini… - Cancer …, 2020 - Wiley Online Library
Since the COVID‐19 outbreak started, it has been affecting mainly older individuals. Among
the most vulnerable older individuals are those with cancer. Many published guidelines and …

Evidence‐practice gaps in lung cancer: A scoping review

NM Rankin, D McGregor, E Stone… - European journal of …, 2018 - Wiley Online Library
Lung cancer is a significant international health problem. Aligning clinical practice with
evidence‐based guideline recommendations has the potential to improve patient outcomes …

Treatment of elderly patients with non–small-cell lung cancer: results of an international expert panel meeting of the Italian Association of Thoracic Oncology

C Gridelli, L Balducci, F Ciardiello, M Di Maio… - Clinical Lung Cancer, 2015 - Elsevier
Most patients with non–small-cell lung cancer (NSCLC) are elderly, and age has important
implications for their management and treatment. In May 2014, the Italian Association of …

Non–small-cell lung cancer in elderly patients: a discussion of treatment options

A Gajra, A Jatoi - Journal of Clinical Oncology, 2014 - ascopubs.org
Lung cancer is a disease of the elderly. In older patients, the management of a malignancy
as complex and potentially as lethal as lung cancer is challenging. Despite the fact that a …

Radical cystectomy and adjuvant chemotherapy for bladder cancer in the elderly: a population-based study

MJ Leveridge, DR Siemens, WJ Mackillop, Y Peng… - Urology, 2015 - Elsevier
Objective To assess radical cystectomy (RC) outcomes and adjuvant chemotherapy (ACT)
use in the elderly in routine practice. Bladder cancer occurs most commonly in the elderly …