Osteoarthritis: pathogenic signaling pathways and therapeutic targets

Q Yao, X Wu, C Tao, W Gong, M Chen, M Qu… - Signal transduction and …, 2023 - nature.com
Osteoarthritis (OA) is a chronic degenerative joint disorder that leads to disability and affects
more than 500 million population worldwide. OA was believed to be caused by the wearing …

[HTML][HTML] Epidemiology of osteoarthritis

KD Allen, LM Thoma, YM Golightly - Osteoarthritis and cartilage, 2022 - Elsevier
Objective To summarize the current state of the evidence regarding osteoarthritis (OA)
prevalence, incidence and risk factors at the person-level and joint-level. Design This was a …

Global, regional prevalence, incidence and risk factors of knee osteoarthritis in population-based studies

A Cui, H Li, D Wang, J Zhong, Y Chen, H Lu - EClinicalMedicine, 2020 - thelancet.com
Background Knee osteoarthritis (OA) is a major cause of disability in the elderly, however,
there are few studies to estimate the global prevalence, incidence, and risk factors of knee …

[HTML][HTML] The role of metabolism in chondrocyte dysfunction and the progression of osteoarthritis

L Zheng, Z Zhang, P Sheng, A Mobasheri - Ageing research reviews, 2021 - Elsevier
Osteoarthritis (OA) is a degenerative joint disease characterized by low-grade inflammation
and high levels of clinical heterogeneity. Aberrant chondrocyte metabolism is a response to …

Global, regional, and national burden of osteoarthritis, 1990–2020 and projections to 2050: a systematic analysis for the Global Burden of Disease Study 2021

JD Steinmetz, GT Culbreth, LM Haile… - The Lancet …, 2023 - thelancet.com
Background Osteoarthritis is the most common form of arthritis in adults, characterised by
chronic pain and loss of mobility. Osteoarthritis most frequently occurs after age 40 years …

Prevalence of obstructive sleep apnea in the general population: a systematic review

CV Senaratna, JL Perret, CJ Lodge, AJ Lowe… - Sleep medicine …, 2017 - Elsevier
With this systematic review we aimed to determine the prevalence of obstructive sleep
apnea (OSA) in adults in the general population and how it varied between population sub …

Platelet-rich plasma: a narrative review

T Collins, D Alexander, B Barkatali - EFORT open reviews, 2021 - eor.bioscientifica.com
The aim of this article was to synopsize platelet-rich plasma (PRP) use in musculoskeletal
pathologies through evidence-based assessment of the preparation, classification …

Update on the epidemiology, risk factors and disease outcomes of osteoarthritis

TW O'Neill, PS McCabe, J McBeth - Best practice & research Clinical …, 2018 - Elsevier
Osteoarthritis (OA) is the most frequent form of arthritis and a leading cause of pain and
disability worldwide. OA can affect any synovial joint, although the hip, knee, hand, foot and …

Number of persons with symptomatic knee osteoarthritis in the US: impact of race and ethnicity, age, sex, and obesity

BR Deshpande, JN Katz, DH Solomon… - Arthritis care & …, 2016 - Wiley Online Library
Objective The prevalence of symptomatic knee osteoarthritis (OA) has been increasing over
the past several decades in the US, concurrent with an aging population and the growing …

EULAR recommendations for the non-pharmacological core management of hip and knee osteoarthritis

L Fernandes, KB Hagen, JWJ Bijlsma… - Annals of the …, 2013 - ard.bmj.com
The objective was to develop evidence-based recommendations and a research and
educational agenda for the non-pharmacological management of hip and knee osteoarthritis …