Boron‐Nitrogen Lewis Pairs in the Assembly of Supramolecular Macrocycles, Molecular Cages, Polymers, and 3D Materials
B Chen, F Jäkle - Angewandte Chemie, 2024 - Wiley Online Library
Covering an exceptionally wide range of bond strengths, the dynamic nature and facile
tunability of dative B− N bonds is highly attractive when it comes to the assembly of …
tunability of dative B− N bonds is highly attractive when it comes to the assembly of …
External flash generation of carbenoids enables monodeuteration of dihalomethanes
K Okamoto, R Higuma, K Muta… - … A European Journal, 2023 - Wiley Online Library
In this study, incorporation of one deuterium atom was achieved by H− D exchange of one of
the two identical methylene protons in various dihalomethanes (halogen= Cl, Br, and I) …
the two identical methylene protons in various dihalomethanes (halogen= Cl, Br, and I) …
Flowmicro In‐Line Analysis‐Driven Design of Reactions Mediated by Unstable Intermediates: Flash Monitoring Approach
Y Ashikari, R Yoshioka, Y Yonekura… - … A European Journal, 2024 - Wiley Online Library
The direct observation of reactive intermediates is an important issue for organic synthesis.
However, intermediates with an extreme instability are hard to be monitored by common …
However, intermediates with an extreme instability are hard to be monitored by common …
Synthesis of Deuterated Compounds by Flow Chemistry
S Kamio, K Okamoto, T Yamagishi, A Nagaki - ChemPlusChem, 2024 - Wiley Online Library
Abstract Development of the efficient and practical method for the synthesis of deuterated
compounds which occupies the broadest area among stable isotopes is one of the most …
compounds which occupies the broadest area among stable isotopes is one of the most …
One-Flow Operation via 4-Bromopyridine Enables Flash Synthesis of AChE Inhibitor
H Soutome, Y Kimuro, T Kawaguchi, D Yoo, Y Yao… - …, 2024 - thieme-connect.com
4-Bromopyridine is a building block that can be converted into valuable compounds, but due
to its low stability, it is commercially available in the form of hydrochloride salt. Therefore, the …
to its low stability, it is commercially available in the form of hydrochloride salt. Therefore, the …
Electrocatalytic Reduction of (Hetero) Aryl Halides in a Proton‐Exchange Membrane Reactor and its Application for Deuteration
Y Ashikari, K Mandai, Y Yao, Y Tsuchihashi… - …, 2023 - Wiley Online Library
We developed an electrocatalytic reduction of (hetero) aryl halides under mild conditions
using a proton exchange membrane (PEM) reactor. This approach allows substituting the …
using a proton exchange membrane (PEM) reactor. This approach allows substituting the …
Reaction of Highly Volatile Organic Compounds with Organolithium Species in Flow Microreactor
K Muta, K Okamoto, A Nagaki - Synlett, 2024 - thieme-connect.com
Highly volatile organic compounds (VOCs) with boiling points (bp) around or below room
temperature are generally difficult to manipulate precisely in liquid-phase organic reactions …
temperature are generally difficult to manipulate precisely in liquid-phase organic reactions …
[HTML][HTML] A Review of Inline Infrared and Nuclear Magnetic Resonance Applications in Flow Chemistry
Y Zhang, WK Su - Pharmaceutical Fronts, 2023 - thieme-connect.com
As a safe and efficient synthesis technique, flow chemistry has recently gained attention in
the pharmaceutical, materials, and environmental protection industries. However …
the pharmaceutical, materials, and environmental protection industries. However …
Fully Automated Reaction Operation Driven by Accurate Inline FTIR Analysis based on Linear-Combination Strategy
Y Ashikari, T Tamaki, K Tomite, Y Yonekura - 2024 - chemrxiv.org
To accelerate advancements in organic chemistry research and development, we propose a
fully automated system based on real-time inline analysis performed by Fourier-transform …
fully automated system based on real-time inline analysis performed by Fourier-transform …