[HTML][HTML] Advanced application of stimuli-responsive drug delivery system for inflammatory arthritis treatment
M Zhang, W Hu, C Cai, Y Wu, J Li, S Dong - Materials Today Bio, 2022 - Elsevier
Inflammatory arthritis is a major cause of disability in the elderly. This condition causes joint
pain, loss of function, and deterioration of quality of life, mainly due to osteoarthritis (OA) and …
pain, loss of function, and deterioration of quality of life, mainly due to osteoarthritis (OA) and …
Inflammaging and osteoarthritis
Osteoarthritis is a highly prevalent disease particularly in subjects over 65 years of age
worldwide. While in the past it was considered a mere consequence of cartilage degradation …
worldwide. While in the past it was considered a mere consequence of cartilage degradation …
[HTML][HTML] Oxidative stress and inflammation in osteoarthritis pathogenesis: Role of polyphenols
Osteoarthritis (OA) is the most prevalent joint degenerative disease leading to irreversible
structural and functional changes in the joint and is a major cause of disability and reduced …
structural and functional changes in the joint and is a major cause of disability and reduced …
[HTML][HTML] Curcumin exerts chondroprotective effects against osteoarthritis by promoting AMPK/PINK1/Parkin-mediated mitophagy
Z Jin, B Chang, Y Wei, Y Yang, H Zhang, J Liu… - Biomedicine & …, 2022 - Elsevier
Osteoarthritis (OA), a chronic degenerative disease with heterogeneous properties, is
difficult to cure due to its complex pathogenesis. Curcumin possesses excellent anti …
difficult to cure due to its complex pathogenesis. Curcumin possesses excellent anti …
Monocytes, macrophages, and their potential niches in synovial joints–therapeutic targets in post-traumatic osteoarthritis?
Synovial joints are complex structures that enable normal locomotion. Following injury, they
undergo a series of changes, including a prevalent inflammatory response. This increases …
undergo a series of changes, including a prevalent inflammatory response. This increases …
Effects of COVID-19 on the musculoskeletal system: clinician's guide
LK Hasan, B Deadwiler, A Haratian… - Orthopedic Research …, 2021 - Taylor & Francis
The global pandemic caused by SARS-CoV-2, or COVID-19, continues to impact all facets of
daily life. Clinical manifestations of COVID-19 commonly include musculoskeletal symptoms …
daily life. Clinical manifestations of COVID-19 commonly include musculoskeletal symptoms …
Effects of interleukin-1β inhibition on incident hip and knee replacement: exploratory analyses from a randomized, double-blind, placebo-controlled trial
M Schieker, PG Conaghan, L Mindeholm… - Annals of internal …, 2020 - acpjournals.org
Background: Osteoarthritis is a common inflammatory disorder with no disease-modifying
therapies. Whether inhibition of interleukin-1β (IL-1β) can reduce the consequences of large …
therapies. Whether inhibition of interleukin-1β (IL-1β) can reduce the consequences of large …
FoxO1 is a crucial mediator of TGF-β/TAK1 signaling and protects against osteoarthritis by maintaining articular cartilage homeostasis
C Wang, J Shen, J Ying, D Xiao… - Proceedings of the …, 2020 - National Acad Sciences
Transforming growth factor-β (TGF-β) signaling is a critical regulator for articular cartilage
tissue maintenance and chondrocyte homeostasis. Nonetheless, the regulatory networks …
tissue maintenance and chondrocyte homeostasis. Nonetheless, the regulatory networks …
[HTML][HTML] Epigenetic alterations and inflammation as emerging use for the advancement of treatment in non-small cell lung cancer
Lung cancer remains one of the most common malignancies in the world. Nowadays, the
most common lung cancer is non-small cell lung cancer (NSCLC), namely …
most common lung cancer is non-small cell lung cancer (NSCLC), namely …
Current understanding of osteoarthritis pathogenesis and relevant new approaches
Osteoarthritis (OA) is the most common degenerative joint disease that causes painful
swelling and permanent damage to the joints in the body. The molecular mechanisms of OA …
swelling and permanent damage to the joints in the body. The molecular mechanisms of OA …