Influence of the nutritional status and oxidative stress in the desaturation and elongation of n-3 and n-6 polyunsaturated fatty acids: Impact on non-alcoholic fatty liver …

LA Videla, MC Hernandez-Rodas, AH Metherel… - … and Essential Fatty …, 2022 - Elsevier
Polyunsaturated fatty acids (PUFA) play essential roles in cell membrane structure and
physiological processes including signal transduction, cellular metabolism and tissue …

Diagnostic and therapeutic strategies for non-alcoholic fatty liver disease

Y Fu, Y Zhou, L Shen, X Li, H Zhang, Y Cui… - Frontiers in …, 2022 - frontiersin.org
The global incidence rate of non-alcoholic fatty liver disease (NAFLD) is approximately 25%.
With the global increase in obesity and its associated metabolic syndromes, NAFLD has …

DHA-enriched phosphatidylserine alleviates high fat diet-induced jejunum injury in mice by modulating gut microbiota

S Tian, Y Zhao, L Qian, S Jiang, Y Tang, T Han - Food & Function, 2023 - pubs.rsc.org
A long-term high-fat diet (HFD) is one of the high-risk factors for intestinal barrier damage.
Docosahexaenoic acid-enriched phosphatidylserine (DHA-PS) has multiple biological …

What's new in the treatment of non-alcoholic fatty liver disease (NAFLD)

M Kosmalski, R Frankowski, S Ziółkowska… - Journal of Clinical …, 2023 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is a serious health problem due to its high
incidence and consequences. In view of the existing controversies, new therapeutic options …

Eicosanoids and other oxylipins in liver injury, inflammation and liver cancer development

MM Alba, B Ebright, B Hua, I Slarve, Y Zhou… - Frontiers in …, 2023 - frontiersin.org
Liver cancer is a malignancy developed from underlying liver disease that encompasses
liver injury and metabolic disorders. The progression from these underlying liver disease to …

Mediterranean diet enriched in extra-virgin olive oil or nuts modulates circulating exosomal non-coding RNAs

DC Mantilla-Escalante, MC Lopez De las Hazas… - European Journal of …, 2021 - Springer
Purpose Exosomes are extracellular vesicles secreted by cells, which can transport different
molecules, including nucleic acids. Dietary habits may induce gene regulation through the …

A crosstalk between epigenetic modulations and non-alcoholic fatty liver disease progression

M Ramezani, M Zobeiry, S Abdolahi, B Hatami… - … -Research and Practice, 2023 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) has recently emerged as a major public health
concern worldwide due to its rapidly rising prevalence and its potential to progress into end …

The effects of nutritional interventions in patients with non-alcoholic fatty liver disease: An umbrella review of meta-analyses of randomized controlled trials

L Sun, H Chen, Q Ou, X Liang, Q Wu, X Yu… - Trends in Food Science …, 2023 - Elsevier
Background Currently, there are no recognized interventions for the prevention and
treatment of non-alcoholic fatty liver disease (NAFLD). Systematic reviews and meta …

Navigating nonalcoholic fatty liver disease (NAFLD): Exploring the roles of estrogens, pharmacological and medical interventions, and life style

Q Zuo, NH Park, JK Lee, A Santaliz-Casiano… - Steroids, 2024 - Elsevier
The pursuit of studying this subject is driven by the urgency to address the increasing global
prevalence of Non-Alcoholic Fatty Liver Disease (NAFLD) and its profound health …

Hepatic unsaturated fatty acids are linked to lower degree of fibrosis in non-alcoholic fatty liver disease

M Fridén, F Rosqvist, H Ahlström, HG Niessen… - Frontiers in …, 2022 - frontiersin.org
Background: The hepatic lipidome of patients with early stages of non-alcoholic fatty liver
disease (NAFLD) has been fairly well-explored. However, studies on more progressive …