Gender differences in the cardiovascular effect of sex hormones

C Vitale, ME Mendelsohn, GMC Rosano - Nature Reviews Cardiology, 2009 - nature.com
The higher incidence of cardiovascular disease in men than in women of similar age, and
the menopause-associated increase in cardiovascular disease in women, has led to …

Gender differences in cardiovascular disease: hormonal and biochemical influences

FR Pérez-López, L Larrad-Mur, A Kallen… - Reproductive …, 2010 - Springer
Objective Atherosclerosis is a complex process characterized by an increase in vascular
wall thickness owing to the accumulation of cells and extracellular matrix between the …

Progesterone antagonizes the vasoprotective effect of estrogen on antioxidant enzyme expression and function

K Wassmann, S Wassmann, G Nickenig - Circulation research, 2005 - Am Heart Assoc
Oxidative stress plays an important role in the pathogenesis of atherosclerosis and can be
effectively influenced by radical scavenging enzymes. Estrogens exert antioxidative effects …

Nomegestrol acetate, a novel progestogen for oral contraception

AO Mueck, R Sitruk-Ware - Steroids, 2011 - Elsevier
Nomegestrol acetate (NOMAC) is a potent, highly selective progestogen, which is
structurally similar to 19-norprogesterone and characterized as a full agonist at the …

The role of gender in coronary surgery

JD Blasberg, GS Schwartz… - European journal of …, 2011 - academic.oup.com
Gender-based outcome data in coronary artery bypass graft (CABG) surgery has been the
focus of extensive research over the last two decades. Increased awareness in gender …

Variations in carotid arterial compliance during the menstrual cycle in young women

K Hayashi, M Miyachi, N Seno… - Experimental …, 2006 - Wiley Online Library
The effect of menstrual cycle phase on arterial elasticity is controversial. In 10 healthy
women (20.6±1.5 years old, mean±sd), we investigated the variations in central and …

Effect of hormone therapy and calcitriol on serum lipid profile in postmenopausal older women: association with estrogen receptor-α genotypes

AJ Sai, JC Gallagher, X Fang - Menopause, 2011 - journals.lww.com
Objective: The aim of this study was to examine the effect of conjugated equine estrogens
alone (ET), conjugated equine estrogens+ medroxyprogesterone (EPT), calcitriol alone …

Estrogen increases iNOS expression in the ovine coronary artery

JL Mershon, RS Baker… - American Journal of …, 2002 - journals.physiology.org
Estrogen is believed to protect postmenopausal women from coronary vascular disease, in
part by increasing production of nitric oxide (NO). In this study, we investigated the possibility …

Randomized trial of effects of continuous combined HRT on markers of lipids and coagulation in women with acute coronary syndromes: WHISP Pilot Study

P Collins, M Flather, B Lees, R Mister… - European heart …, 2006 - academic.oup.com
Aims Randomized trials have not demonstrated coronary heart disease benefit from
hormone replacement therapy (HRT). We hypothesized that low-dose HRT may avoid harm …

New insights into nitric oxide and coronary circulation

D Gattullo, P Pagliaro, NA Marsh, G Losano - Life sciences, 1999 - Elsevier
Since its discovery over 20 years ago as an intercellular messenger, nitric oxide (NO), has
been extensively studied with regard to its involvement in the control of the circulation and …