[HTML][HTML] Inflammation, epigenetics, and metabolism converge to cell senescence and ageing: the regulation and intervention
X Zhu, Z Chen, W Shen, G Huang, JM Sedivy… - Signal transduction and …, 2021 - nature.com
Remarkable progress in ageing research has been achieved over the past decades.
General perceptions and experimental evidence pinpoint that the decline of physical …
General perceptions and experimental evidence pinpoint that the decline of physical …
[HTML][HTML] The role of inflammation in age-related sarcopenia
Many physiological changes occur with aging. These changes often, directly or indirectly,
result in a deterioration of the quality of life and even in a shortening of life expectancy …
result in a deterioration of the quality of life and even in a shortening of life expectancy …
Opportunities and challenges of radiotherapy for treating cancer
D Schaue, WH McBride - Nature reviews Clinical oncology, 2015 - nature.com
The past 20 years have seen dramatic changes in the delivery of radiation therapy, but the
impact of radiobiology on the clinic has been far less substantial. A major consideration in …
impact of radiobiology on the clinic has been far less substantial. A major consideration in …
[HTML][HTML] Redox mechanism of reactive oxygen species in exercise
F He, J Li, Z Liu, CC Chuang, W Yang, L Zuo - Frontiers in physiology, 2016 - frontiersin.org
It is well known that regular exercise can benefit health by enhancing antioxidant defenses
in the body. However, unaccustomed and/or exhaustive exercise can generate excessive …
in the body. However, unaccustomed and/or exhaustive exercise can generate excessive …
Polystyrene microplastics-induced ROS overproduction disrupts the skeletal muscle regeneration by converting myoblasts into adipocytes
W Shengchen, L Jing, Y Yujie, W Yue… - Journal of hazardous …, 2021 - Elsevier
The environmental problem of Microplastics (MPs) pollution poses a great threat to human
and animal health, which has attracted global attention. The physiological integrity of …
and animal health, which has attracted global attention. The physiological integrity of …
[HTML][HTML] The role of oxidative stress in the pathogenesis of infections with coronaviruses
Coronaviruses can cause serious respiratory tract infections and may also impact other end
organs such as the central nervous system, the lung and the heart. The coronavirus disease …
organs such as the central nervous system, the lung and the heart. The coronavirus disease …
The mechanisms of muscle hypertrophy and their application to resistance training
BJ Schoenfeld - The Journal of Strength & Conditioning Research, 2010 - journals.lww.com
Schoenfeld, BJ. The mechanisms of muscle hypertrophy and their application to resistance
training. J Strength Cond Res 24 (10): 2857-2875, 2010-The quest to increase lean body …
training. J Strength Cond Res 24 (10): 2857-2875, 2010-The quest to increase lean body …
Potential mechanisms for a role of metabolic stress in hypertrophic adaptations to resistance training
BJ Schoenfeld - Sports medicine, 2013 - Springer
It is well established that regimented resistance training can promote increases in muscle
hypertrophy. The prevailing body of research indicates that mechanical stress is the primary …
hypertrophy. The prevailing body of research indicates that mechanical stress is the primary …
Mechanisms and functions of p38 MAPK signalling
A Cuadrado, AR Nebreda - Biochemical journal, 2010 - portlandpress.com
The p38 MAPK (mitogen-activated protein kinase) signalling pathway allows cells to
interpret a wide range of external signals and respond appropriately by generating a …
interpret a wide range of external signals and respond appropriately by generating a …
[HTML][HTML] Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP)
A Salminen, A Kauppinen, K Kaarniranta - Cellular signalling, 2012 - Elsevier
The major hallmark of cellular senescence is an irreversible cell cycle arrest and thus it is a
potent tumor suppressor mechanism. Genotoxic insults, eg oxidative stress, are important …
potent tumor suppressor mechanism. Genotoxic insults, eg oxidative stress, are important …