[HTML][HTML] Inflammation, epigenetics, and metabolism converge to cell senescence and ageing: the regulation and intervention

X Zhu, Z Chen, W Shen, G Huang, JM Sedivy… - Signal transduction and …, 2021 - nature.com
Remarkable progress in ageing research has been achieved over the past decades.
General perceptions and experimental evidence pinpoint that the decline of physical …

[HTML][HTML] The role of inflammation in age-related sarcopenia

S Dalle, L Rossmeislova, K Koppo - Frontiers in physiology, 2017 - frontiersin.org
Many physiological changes occur with aging. These changes often, directly or indirectly,
result in a deterioration of the quality of life and even in a shortening of life expectancy …

Opportunities and challenges of radiotherapy for treating cancer

D Schaue, WH McBride - Nature reviews Clinical oncology, 2015 - nature.com
The past 20 years have seen dramatic changes in the delivery of radiation therapy, but the
impact of radiobiology on the clinic has been far less substantial. A major consideration in …

[HTML][HTML] Redox mechanism of reactive oxygen species in exercise

F He, J Li, Z Liu, CC Chuang, W Yang, L Zuo - Frontiers in physiology, 2016 - frontiersin.org
It is well known that regular exercise can benefit health by enhancing antioxidant defenses
in the body. However, unaccustomed and/or exhaustive exercise can generate excessive …

Polystyrene microplastics-induced ROS overproduction disrupts the skeletal muscle regeneration by converting myoblasts into adipocytes

W Shengchen, L Jing, Y Yujie, W Yue… - Journal of hazardous …, 2021 - Elsevier
The environmental problem of Microplastics (MPs) pollution poses a great threat to human
and animal health, which has attracted global attention. The physiological integrity of …

[HTML][HTML] The role of oxidative stress in the pathogenesis of infections with coronaviruses

C Gain, S Song, T Angtuaco, S Satta… - Frontiers in …, 2023 - frontiersin.org
Coronaviruses can cause serious respiratory tract infections and may also impact other end
organs such as the central nervous system, the lung and the heart. The coronavirus disease …

The mechanisms of muscle hypertrophy and their application to resistance training

BJ Schoenfeld - The Journal of Strength & Conditioning Research, 2010 - journals.lww.com
Schoenfeld, BJ. The mechanisms of muscle hypertrophy and their application to resistance
training. J Strength Cond Res 24 (10): 2857-2875, 2010-The quest to increase lean body …

Potential mechanisms for a role of metabolic stress in hypertrophic adaptations to resistance training

BJ Schoenfeld - Sports medicine, 2013 - Springer
It is well established that regimented resistance training can promote increases in muscle
hypertrophy. The prevailing body of research indicates that mechanical stress is the primary …

Mechanisms and functions of p38 MAPK signalling

A Cuadrado, AR Nebreda - Biochemical journal, 2010 - portlandpress.com
The p38 MAPK (mitogen-activated protein kinase) signalling pathway allows cells to
interpret a wide range of external signals and respond appropriately by generating a …

[HTML][HTML] Emerging role of NF-κB signaling in the induction of senescence-associated secretory phenotype (SASP)

A Salminen, A Kauppinen, K Kaarniranta - Cellular signalling, 2012 - Elsevier
The major hallmark of cellular senescence is an irreversible cell cycle arrest and thus it is a
potent tumor suppressor mechanism. Genotoxic insults, eg oxidative stress, are important …