Modeling arterial pulse waves in healthy aging: a database for in silico evaluation of hemodynamics and pulse wave indexes
PH Charlton, J Mariscal Harana… - American Journal …, 2019 - journals.physiology.org
The arterial pulse wave (PW) is a rich source of information on cardiovascular (CV) health. It
is widely measured by both consumer and clinical devices. However, the physical …
is widely measured by both consumer and clinical devices. However, the physical …
Assessing hemodynamics from the photoplethysmogram to gain insights into vascular age: a review from VascAgeNet
The photoplethysmogram (PPG) signal is widely measured by clinical and consumer
devices, and it is emerging as a potential tool for assessing vascular age. The shape and …
devices, and it is emerging as a potential tool for assessing vascular age. The shape and …
Towards enabling a cardiovascular digital twin for human systemic circulation using inverse analysis
NK Chakshu, I Sazonov, P Nithiarasu - Biomechanics and modeling in …, 2021 - Springer
An exponential rise in patient data provides an excellent opportunity to improve the existing
health care infrastructure. In the present work, a method to enable cardiovascular digital twin …
health care infrastructure. In the present work, a method to enable cardiovascular digital twin …
Arterial pulse wave modeling and analysis for vascular-age studies: a review from VascAgeNet
Arterial pulse waves (PWs) such as blood pressure and photoplethysmogram (PPG) signals
contain a wealth of information on the cardiovascular (CV) system that can be exploited to …
contain a wealth of information on the cardiovascular (CV) system that can be exploited to …
Extraction of respiratory signals from the electrocardiogram and photoplethysmogram: technical and physiological determinants
PH Charlton, T Bonnici, L Tarassenko… - Physiological …, 2017 - iopscience.iop.org
Objective: Breathing rate (BR) can be estimated by extracting respiratory signals from the
electrocardiogram (ECG) or photoplethysmogram (PPG). The extracted respiratory signals …
electrocardiogram (ECG) or photoplethysmogram (PPG). The extracted respiratory signals …
Creation and application of virtual patient cohorts of heart models
SA Niederer, Y Aboelkassem… - … of the Royal …, 2020 - royalsocietypublishing.org
Patient-specific cardiac models are now being used to guide therapies. The increased use
of patient-specific cardiac simulations in clinical care will give rise to the development of …
of patient-specific cardiac simulations in clinical care will give rise to the development of …
Noninvasive hemodynamic indices of vascular aging: An in silico assessment
J Hong, M Nandi, PH Charlton… - American Journal of …, 2023 - journals.physiology.org
Vascular aging (VA) involves structural and functional changes in blood vessels that
contribute to cardiovascular disease. Several noninvasive pulse wave (PW) indices have …
contribute to cardiovascular disease. Several noninvasive pulse wave (PW) indices have …
Forward and backward pressure waveform morphology in hypertension
Y Li, H Gu, H Fok, J Alastruey, P Chowienczyk - Hypertension, 2017 - Am Heart Assoc
We tested the hypothesis that increased pulse wave reflection and altered backward
waveform morphology contribute to increased pulse pressure in subjects with higher pulse …
waveform morphology contribute to increased pulse pressure in subjects with higher pulse …
Augmentation index is not a proxy for wave reflection magnitude: mechanistic analysis using a computational model
MHG Heusinkveld, T Delhaas… - Journal of Applied …, 2019 - journals.physiology.org
The augmentation index (AIx) is deemed to capture the deleterious effect on left ventricular
(LV) work of increased wave reflection associated with stiffer arteries. However, its validity as …
(LV) work of increased wave reflection associated with stiffer arteries. However, its validity as …
What is needed to make cardiovascular models suitable for clinical decision support? A viewpoint paper
W Huberts, SGH Heinen, N Zonnebeld… - Journal of computational …, 2018 - Elsevier
The potential impact of hemodynamic and vascular wall models on the diagnosis, treatment,
and well-being of thousands of patients suffering from cardiovascular diseases, is …
and well-being of thousands of patients suffering from cardiovascular diseases, is …